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多西环素联合沙利度胺治疗硬结型、囊肿型痤疮的临床观察
多西环素联合沙利度胺治疗硬结型、囊肿型痤疮的临床观察
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摘要
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DOI
ojn3q19mdr/3371513
作者
贾真
机构地区
多西环素联合沙利度胺治疗硬结型、囊肿型痤疮的临床观察 贾 真 （北京京北职业技术学院 北京 101400） 【摘 要】目的：评价多西环素、沙利度胺联合多西环素治疗硬结型、囊肿型痤疮的临床疗效及安全性。方法：按照纳入标准选择70名硬结型、囊肿型患者，随机分为对照组（仅用多西环素）和治疗组（多西环素联合沙利度胺）、开放对照、定期观察。结果：治疗3周两组的有效率无统计学意义差异（P>0.05），治疗8周后，两组的有效率分别为54.3%和82.9%，有统计学差异（P<0.05）。结论：沙利度胺联合多西环素治疗硬结型、囊肿型痤疮的疗效优于单一服用多西环素，未出现严重的副反应。 【
出处
《中国保健营养》
2019年1期
关键词
痤疮
沙利度胺，多西环素
中图分类号R758.734
文献标识码A
文章编号1004-7484（2019）01-0079-02
Clinical
observation
of
combination
therapy
with
doxycycline
and
Thalidomide
in
the
treatment
of
indurate
and
cystic
acne
AbstractObjective
To
evaluate
the
efficacy
and
safety
of
combination
therapy
with
doxycycline
and
Thalidomide
in
the
treatment
of
indurate
and
cystic
acne.
Methods
Seventy
patients
were
randomized
into
two
groups
treatment
group(n=35)
and
control
group(n=35).The
control
group
was
treated
with
doxycycline
the
treatment
group
was
treated
with
doxycycline
and
Thalidomide.
The
observation
periods
were
three
weeks
and
eight
weeks
open
control.
Results
After
three
weeks
there
was
no
significant
difference(P>
0.05)
between
two
groups.
Eight
weeks
later
the
response
rate
was
54.3%
for
control
group
and
82.9%
for
treatment
group
showing
significant
differences
(P<
0.05)
between
two
groups.
Conclusions
doxycycline
combined
with
Thalidomide
have
significant
clinical
effect
comparing
to
分类
[医药卫生][公共卫生与预防医学]
出版日期
2019年01月11日（中国期刊网平台首次上网日期，不代表论文的发表时间）
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2
陈,哲,1张海丽,2侯立影,3.
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3
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4
何架英.
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.中西医结合,2018-05.
5
杨冠香邓列华(通讯作者).
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6
徐辉.
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.公共卫生与预防医学,2019-07.
7
薛丽.
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.卫生事业管理,2018-12.
8
陈桂升;翟晓翔;单霄.
中药联合光动力疗法治疗囊肿型痤疮临床观察
.皮肤病学与性病学,2017-06.
9
蒋小燕.
多西环素联合过氧苯甲酰凝胶治疗寻常痤疮的疗效观察
.医学心理学,2018-12.
10
宋文韬.
寻常型痤疮使用龙珠软膏与多西环素片疗效分析
.免疫学,2013-04.
来源期刊
中国保健营养
2019年1期
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相关关键词
痤疮
沙利度胺，多西环素
中图分类号R758.734
文献标识码A
文章编号1004-7484（2019）01-0079-02
Clinical
observation
of
combination
therapy
with
doxycycline
and
Thalidomide
in
the
treatment
of
indurate
and
cystic
acne
AbstractObjective
To
evaluate
the
efficacy
and
safety
of
combination
therapy
with
doxycycline
and
Thalidomide
in
the
treatment
of
indurate
and
cystic
acne.
Methods
Seventy
patients
were
randomized
into
two
groups
treatment
group(n=35)
and
control
group(n=35).The
control
group
was
treated
with
doxycycline
the
treatment
group
was
treated
with
doxycycline
and
Thalidomide.
The
observation
periods
were
three
weeks
and
eight
weeks
open
control.
Results
After
three
weeks
there
was
no
significant
difference(P>
0.05)
between
two
groups.
Eight
weeks
later
the
response
rate
was
54.3%
for
control
group
and
82.9%
for
treatment
group
showing
significant
differences
(P<
0.05)
between
two
groups.
Conclusions
doxycycline
combined
with
Thalidomide
have
significant
clinical
effect
comparing
to
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