摘要
Toobservetheprocessofinvasion,retinaofratwasusedasamodeltosubstitutetheinnerlimitingmembraneofretinaforthebasementmembrane.RetinainvadedbyesophagealcarcinomacellsandB16melanomacellsupontheinnerlimitingmembranewasstudiedbyscanningandtransmissionelectronmicroscopy.Theresultsshowedthattheinnerlimitingmembranewasdestroyedbybothkindsoftumorcells.Theprocessofdestructionwasfollowedbyaseriesoftransformationsintheinnerlimitingmembrane,i.e.folding,swelling,thickening,andgranularchange.Theinnerlimitingmembranewasdissolvedfocallyasaresultoftransformation,andthentumorcellsinvadedtheretinathroughthesedissolvedregions.Itseemsthat,asabarrier,theinnerlimitingmembraneplaysasimilarroleasthebasementmembrane.
出版日期
1989年03月13日(中国期刊网平台首次上网日期,不代表论文的发表时间)