简介：摘要目的比较小儿七氟烷麻醉中不同剂量瑞芬太尼持续输注对自主呼吸的影响.方法选包皮环切手术患儿为研究对象,随机分为生理盐水对照组、低剂量组、中剂量组、高剂量组,比较四组麻醉效果.结果瑞芬太尼高剂量组RR低于低、中剂量组(P＜０．０５);瑞芬太尼高剂量组T３、T４、T５时MV均低于低剂量组与中剂量组(P＜０．０５).结论选择０．０３－０．０６μg??kg－１??min－１剂量瑞芬太尼持续输注有助于保留患儿自主呼吸.关键词小儿;七氟烷麻醉;瑞芬太尼AcomparedofspontaneousbreathingofdifferentdosesremifentanilcontinuousinfusioninchildrensevofluraneanesthesiaAbstractObjectiveTocomparesevofluraneanesthesiainchildrenofdifferentdosesofremifentanilcontinuousinfusiononspontaneousbreathing．Methodscircumcisionsurgeryinchildrenforthestudywererandomlydividedintosalinecontrolgroup,lowdosegroup,middledosegroup,highdosegroup,thefourgroupsofanesthesia．ResultsremifentanilRRbelowthelowandhighdosegroup,middledosegroup(P＜０．０５);remifentanilhighdosegroupT３,T４,T５whenMVwerelowerthanthelow－dosegroupandmiddledosegroup(P＜０．０５)．ConclusionSelect０．０３－０．０６μg??kg－１??min－１dosecontinuousinfusionofremifentanilhelpprKeesyerwvoercdhsildrenwithspontaneousbreathing．Children;Refentanil;Sevoflurane中图分类号R７２６．１文献标识码B文章编号１００８－６３１５(２０１５)１２－１２２８－０１