简介：Wehavepreviouslydevelopedacombinedsignal/variancedistributionmodelthataccountsfortheparticularstatisticalpropertiesofdatasetsgeneratedontheAp-pliedBiosystemsAB1700transcriptomesystem.Hereweshowthatthismodelcanbeefficientlyusedtogeneratesyntheticdatasetswithstatisticalpropertiesvirtu-allyidenticaltothoseoftheactualdatabyaidoftheJAVAapplicationace.mapcreator1.0thatwehavedeveloped.ThefundamentallydifferentstructureofAB1700transcriptomeprofilesrequiresre-evaluation,adaptation,orevenrede-velopmentofmanyofthestandardmicroarrayanalysismethodsinordertoavoidmisinterpretationofthedataontheonehand,andtodrawfullbenefitfromtheirincreasedspecificityandsensitivityontheotherhand.Ourcompositedatamodelandtheace.mapcreator1.0applicationtherebynotonlypresentproofofthecor-rectnessofourparameterestimation,butalsoprovideatoolforthegenerationofsynthetictestdatathatwillbeusefulforfurtherdevelopmentandtestingofanalysismethods.