简介：BACKGROUND:Gliomaisthemostcommonintracranialtumorandhasapoorpatientprognosis.Thepresenceofbraintumorstemcellswasgraduallybeingunderstoodandrecognized,whichmightbebeneficialforthetreatmentofglioma.OBJECTIVE:Tousebibliometricindexestotrackstudyfocusesongliomastemcell,andtoinvestigatetherelationshipsamonggeographicorigin,impactfactors,andhighlycitedarticlesindexedinWebofScience.METHODS:AlistofcitationclassicsforgliomastemcellswasgeneratedbysearchingthedatabaseofWebofScience-Expandedusingtheterms"gliomastemcell"or"glioma,stemcell’"or"braintumorstemcell".Thetop63citedresearcharticleswhichwerecitedmorethan100timeswereretrievedbyreadingtheabstractorfulltextifneeded.Eacheligiblearticlewasreviewedforbasicinformationonsubjectcategories,countryoforigin,journals,authors,andsourceofjournals.Inclusivecriteria:(1)articlesinthefieldofgliomastemcellswhichwascitedmorethan100times;(2)fundamentalresearchonhumansoranimals,clinicaltrialsandcasereports;(3)researcharticle;(4)yearofpublication:1899-2012;and(5)citationdatabase:ScienceCitationIndex-Expanded.Exclusivecriteria:(1)articlesneedingtobemanuallysearchedoraccessedonlybytelephone;(2)unpublishedarticles;and(3)reviews,conferenceproceedings,aswellascorrectedpapers.RESULTS:Of2040articlespublished,the63top-citedarticleswerepublishedbetween1992and2010.Thenumberofcitationsrangedfrom100to1754,withameanof280citationsperarticle.Thesecitationclassicscamefromnineteencountries,ofwhich46articlescamefromtheUnitedStates.DukeUniversityandUniversityofCalifornia,SanFranciscoledthelistofclassicswithsevenpaperseach.The63top-citedarticleswerepublishedin28journals,predominantlyCancerResearchandCancerCell,followedbyCellStemCellandNature.CONCLUSION:Ourbibliometricanalysisprovidesahistoricalpersp