简介:我科收治的患眼无视功能患者25例,保留自体巩膜壳,行羟基磷灰石义眼台植入术,现报告如下。
简介:AIM:Toreportthecytologyresultsof25-gaugetransconjunctival(25G-TSV)diagnosticvitrectomyincasessuspiciousforintraocularlymphoma(IOL),andcomparetheresultstothosereportedintheliterature.METHODS:Clinicalandcytopathologicalrecordsof18vitreousbiopsyspecimensobtainedvia25G-TSVdiagnosticvitrectomyin12patientssuspiciousforIOLwerereviewedretrospectively.Areviewoftheliteratureinregardstothediagnosticyieldsofvitreousspecimensobtainedvia25-gaugeand20-gaugediagnosticvitrectomyinsuspectedcasesofIOLwasperformed.RESULTS:Eighteeneyesfrom12patientswithclinicalsuspicionofIOLunderwentdiagnostic25G-TSV.ThecytopathologicalinvestigationsdemonstratedIOLin15eyes(83.3%).Vitreousanalysiswasnon-diagnosticin3eyes(16.7%).CONCLUSION:Twenty-five-gaugediagnosticvitrectomyyieldsadequatesampleforcytologicalevaluationofthevitreousincasessuspiciousforIOL.Thediagnosticresultsofthe25G-TSVinthecurrentstudyaresuperiortothosereportedfor20-gaugevitrectomybutequivalenttothosereportedfor25G-TSVinthepublishedliterature.
简介:AIM:Tocomparetheclinicaloutcomesofcombined25-gaugeparsplanavitrectomy(PPV)andphacoemulsification/posteriorchamberintraocularlens(PC-IOL)implantationwithvitrectomyalonesurgeryinpatientswithvariousvitreoretinaldiseases.METHODS:Atotalof306eyes(145withPPValoneand161withphaco-vitrectomy)wereenrolledinthisretrospectiveanalysis.Thesurgicalapproachwas25-gaugePPVcombinedwithphacoemulsificationandPC-IOLimplantationatthesametimeineyesinphaco-vitrectomygroupandonlyPPVineyesinvitrectomyalonesurgerygroup.Themainoutcomemeasureswerepostoperativeclinicaloutcomesincludedanteriorchamberinflammation,changesinintraocularpressure(IOP)andbestcorrectedvisualacuity(BCVA).RESULTS:Themostcommonpostoperativecomplicationwasanteriorchamberreactionwhichhashigherincidenceinphaco-vitrectomygroup(P<0.001).Themeanpostoperative1stdayIOPofvitrectomyalonegroupwassignificantlylowerthanthatofphaco-vitrectomygroup(16.3±5.8mmHgvs17.8±8.1mmHg,respectively,P=0.02).Hypotony(IOP(8mmHg)wasnotdifferentbetweengroupsinthepostoperative1stday(P>0.05).Themeanpreoperativevisualacuitywasnotdifferentbetweengroups(1.6±0.9logMARvs1.8±0.9logMAR,respectively,P>0.05).However,themeanvisualacuitywasdecreasedinvitrectomyalonegroupatthefinalvisitcomparedtophaco-vitrectomygroup(1.2±0.8logMAR,0.9±0.7logMAR,respectivelyP<0.05).CONCLUSION:Twenty-fivegaugePPVcombinedwithphacoemulsificationsurgeryisasafeandefficientprocedure,whichcanbepreferredinphacicpatientswithavarietyofvitreoretinaldiseasescomparedtovitrectomyalone.Despiteimprovedoutcomes,thisapproachisnotfreeoflimitationsasanteriorchambercomplicationsespeciallywithcombinedsurgery.
简介:目的:探讨术前注射曲安奈德(TA)联合25G微创玻璃体视网膜手术(vitreoretinalsurgery,VRS)治疗增生型糖尿病性视网膜病变(proliferativediabeticretinopathy,PDR)的效果。方法:选取我院眼科需行VRS治疗的PDR患者108例108眼随机分为两组,VRS+TA组:VRS术前1wk行玻璃体腔注射TA的患者54例;VRS组:直接行VRS治疗患者54例,比较两组患者手术情况、术前、术后3mo裸眼视力、最佳矫正视力,术前、术后1wk,1、3mo眼压和并发症情况。结果:VRS+TA组手术时间、电凝率、医源性裂孔率和术中出血率显著短于或低于VRS组,差异有统计学意义(P〈0.05),而两组患者眼内填充物比较无统计学差异(P〉0.05);两组患者术后3mo裸眼视力和最佳矫正视力较术前均得到显著提高,差异有统计学意义(P〈0.05),两组间比较差异无统计学意义(P〉0.05);VRS+TA组术后1、3mo眼压较术前显著升高,差异有统计学意义(P〈0.05),两组间比较差异无统计学意义(P〉0.05);VRS+TA组前房渗出率显著低于VRS组,差异有统计学意义(P〈0.05),但两组并发症总发生率差异无统计学意义(P〉0.05)。结论:PDR患者行VRS治疗前1wk注射TA,可降低手术难度,缩短手术时间,并减少术中、术后并发症,利于患者术后视力改善。
简介:目的探讨一组特殊设计镜片对周边屈光度、周边清晰视力范围和主观感受的影响。方法3例(4眼)被试者,年龄22-31岁,屈光度-2.0D,按随机顺序分别在单眼配戴普通非球面镜片、成长乐镜片、视特保大、中、小光区镜片的情况下进行周边屈光度、周边清晰视力范围测量和主观评分,主观评分包括远距和近距戴镜舒适度、清晰度和接受度。结果配戴5种镜片时,被试眼相对周边屈光度均为远视状态,远视度数随周边角度增加而增加。配戴普通非球面镜片和视特保大光区镜片时周边远视度数最大,视特保中光区镜片其次,成长乐镜片和视特保小光区镜片最小;配戴普通非球面镜片和视特保大光区镜片时的周边清晰视力范围最大,其次是视特保中光区镜片,最小的是成长乐镜片和视特保小光区镜片;远距评分为普通非球面镜片最高,视特保大光区镜片其次,然后为视特保中光区镜片,成长乐镜片及视特保小光区镜片最差;近距评分视特保大光区镜片接近普通非球面镜片,视特保中光区镜片和成长乐镜片其次,视特保小光区镜片最差。结论不同设计的中周部加光镜片对改变周边屈光度的作用存在差异,其配戴后的顺应性与镜片改变周边屈光度的程度呈负相关。
简介:目的观察1,25(OH)2D3对高糖诱导牛视网膜血管内皮细胞(BRECs)中血管内皮生长因子(VEGF)的表达水平变化及对细胞凋亡水平的影响。方法将分离培养的BRECs分为三组,分别为正常糖组、高糖组和高糖处理组。正常对照组细胞培养液含5mmol/L葡萄糖,高糖组细胞培养液含30mmol/L葡萄糖,高糖处理组细胞培养液含30mmol/L葡萄糖和50nM,1,25(OH)2D3。培养48h后收集细胞蛋白。蛋白免疫印迹法检测细胞VEGF及细胞凋亡相关蛋白Bax和Bcl-2表达水平;PI/Hoechst双染色法检测细胞凋亡。结果相比于正常糖组,高糖组中VEFG水平和Bax/Bcl-2比值显著增加;而在高糖处理组中表达水平远远低于高糖组,差异均有统计学意义(P〈0.05)。高糖的细胞凋亡水平高于正常糖组,而经过1,25(OH)2D3处理后,其细胞凋亡水平则有所下降,差异均有统计学意义(P〈0.05)。结论1,25(OH)2D3可以抑制高糖诱导BRECs中VEGF表达增加及细胞凋亡。
简介:准分子激光角膜切削术是九十年代在我国兴起的角膜屈光手术。近年来有诸多成功报道。但是,对于PBK术后的远期疗效乃是医生和患者极为关注的问题。我院自1996年4月开始用PRK治疗近视,效果较好,现对PRK术后5年以上患者进行随诊观察345例671眼,结果报告如下。资料与方法