简介：Heatshockproteins(HSPs),suchasHSP70andHSP90,areasuiteofhighlyconservedproteinsproducedinallcellularorganismswhentheyareexposedtostresses.Inaquaticanimals,theyhavebeenprovedtoplayimportantrolesinresponsetoenvironmentalpollutantsandparticularlyinthenon-specificimmuneresponsestopathogeninfections.Inthepresentstudy,theexpressionprofilesofHSP70andHSP90genesinhemocytesandhepatopancreasfromtheridgetailwhiteprawnExopalaemoncarinicaudainfectedwithWSSVandVibrioanguillarumweredetectedusingreversetranscriptionpolymerasechainreaction(RT-PCR).AfterWSSVchallenge,theexpressionlevelofHSP70genetranscriptsinthehemocytesandhepatopancreasincreasedtopeaklevelat6hand48h,respectively.HSP90genetranscriptsinhemocytesandhepatopancreaswereup-regulatedsignificantlyat12hand6h,respectively.DuringV.anguillarumchallenge,themRNAcontentofHSP70geneinhemocytesandhepatopancreasincreasedsignificantlyat12hand6hpost-infection,respectively.TheexpressionlevelofHSP90genebothinhemocytesandhepatopancreaswereup-regulatedinthefirst3h.TheexpressionpatternsofHSP70andHSP90genesinhemocytesandhepatopancreasshowedtemporalandspatialdifferencesafterchallengedwithWSSVandV.anguillarum.TheresultssuggestedthatHSPsmightbeinvolvedinimmuneresponsestopathogenschallengeinE.carinicauda.