简介:Theaimofthisstudyistoreportandanalyzethefactorsrelatedwithearlieroccurrenceofsiliconeoil(SO)emulsificationinpatientsunderwentparsplanavitrectomyandSOinjectioninourhospital.WeretrospectivelyreviewedconsecutivecaseseriesundergonebothSOinjectionandremovalinourhospital,and182oneswereeligible.Possiblerelatedindependentfactorsincluded:maculastatus(on/off),concomitantphacoemulsificationwiththesurgeryofSOtamponading,concomitantstatusofproliferativevitreoretinopathy,combinedsurgeryofretinotomy,timetohaveemulsification(<6mo/≥6moafterprimarySOinjection),routeofSOinjection(anterior/posterior),lensstatus(aphakic/pseudophakic/phakic),anesthesia(local/general),brandsandtypeofSO,with/withoutepiscleralcryotherapy,with/withouthypertension,with/withoutdiabetes,with/withoutintraoperativeuseoftriamcinoloneacetonide.ThestudyrevealedthatbrandandtypeofSOwasthesignificantfactorrelatedwithearlieremulsificationofSO.Furtherstudywaswarrantedtofindouttheunderlyingcauses.
简介:AIMTo在在为复杂网膜的detachment.METHODSWe经历retinectomy的病人的硅酮油(ROSO)的移动执行了为复杂网膜的分开在retinectomy以后经历了ROSO的病人的回顾的盒子笔记评论以后,评估功能的结果。有不到6mo的病人列在后面在上面并且周期性的网膜的分开追随者ROSO是excluded.RESULTSThirty--六个病人被包括。吝啬的最好改正的视觉尖酸(BCVA)pre-ROSO是1.13logMAR(SD0.5)。吝啬的BCVA3mo追随者ROSO是1.16logMAR(SD0.53),6mo追随者ROSO1.13(SD0.63),和跟随ROSO1.18(SD0.69)的12mo。在在ROSO以后的12mo,BCVA在38.9%病人改善了,在25%仍然保持未改变,并且尽管在在在3点的ROSO以后的BCVA没有统计重要差别,在36.1%败坏了,6并且12mo(P=0.93)。retinectomy的尺寸从15°;到270°;(SD53)并且没影响.CONCLUSIONThere是的视觉结果(P=0.11)在在pre-和柱子之间的BCVA的没有统计上重要的差别--为复杂网膜的分开的ROSO后面的retinectomy。在与retinectomy的尺寸有关的视觉结果没有统计差别。
简介:疼痛追随者仓库肌内(IM)油的注射基于车辆的药是学习的很少。这研究试图有希望地在4-mL海狸油车辆在1000mg睾丸激素undecanoate(TU)的IM注射以后在这个星期期间决定流行,决定因素,严厉和疼痛的功能的后果。在一个学术andrology诊所收到常规T代替治疗的雄激素缺乏的人被招募在深IM臀的注射以后在第一天和日报在七次用有色的视觉线性类似物规模报导疼痛分数一个星期。时间功课和covariables影响疼痛分数被变化(ANOVA)的混合模型分析分析。在125个人,的追随者168注射疼痛被80%人报导,在注射以后立即达到顶点,到达仅仅中等的严厉,持续1鈥?天并且在白天回到基线4。疼痛几乎没要求很少止痛使用并且在每日的活动生产了最小的干扰。疼痛分数的时间功课在经历了二连续注射的43个人是可再现的。疼痛在有更早痛苦的注射,而是在严重的更少的人是更严重的更旧并且更多的肥胖的人。根据在管理注射的富有经验的护士之间的注射以后的疼痛经验有可以忽略的差别。在4-mL海狸油的仓库TU的深IM臀的注射很好被容忍,注射以后的疼痛被更早痛苦的注射经验,以及年龄和肥胖影响。
简介:在这研究,二商业地可得到的superoxidescavengers,tetrakis(1-methyl-4-pyridyl)卟啉(Mn[III]TMPyP)并且superoxidedismutase(草皮),以及红手掌油(RPO),自然蔬菜油,被用来调查他们的在对人的精子活动性上的superoxide(O2)的有毒的效果的vitro效果可能。精液样品从健康志愿者施主在19和23年之间变老的12normozoospermic被获得。O2施主2,3-dimetoxyl-1,4-naphthoquinone(DMNQ)(2.5摩尔L-1鈥?00摩尔L-1)当面被加到normozoospermicpost-swim-up精子或Mn(III)TMPyP(50摩尔L-1)的缺席,草皮(50IU)或RPO(0.1%或0.5%)。帮助计算机的精液分析被用来分析各种各样的活动性参数。兴趣的参数是能动房间,进步活动性,快速的房间和静态的房间的百分比。集中高对精子活动性比25摩尔L-1DMNQ有害。Mn(III)TMPyP能在活动性参数上稀释O2的效果。在vitro,草皮和RPO的增加在精子活动性上显示出有害效果。
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简介:Thisexperimentusedwhole-cellpatch-clamptechniquetoinvestigatethecourseofrecoveryfromuse-dependentblockofNa+channels(Nav1.5)inhumanembryonickidney(HEK)cells,onwhichtoverifytheeffectsofvolatileoilofNardostachychinesisBatal(Gansong).MethodsTwopulsesgeneratedbycomputerfollowedbyarecoverypulseandatestpulse,theintervaldurationbetweenthetwopulsesvariedfrom16msto1s,andholdingpotentialis-80mVto-140mV.ThepeakNa+currentforagivenrecoverytimewasnormalizedtothefullyrecoveredpeakcurrent,andthenormalizedvaluewastheplotasafunctionoftherecoverytimetostudytheeffectsof3ppmconcentrationGansongvolatileoilonrecoveryfromuse-dependentblockofNav1.5inHEK.ResultsItshowedthatGansonggroup,comparingwithcontrolgroup,delayedthetimecoursesofrecoveryfromuse-dependentblock[(33.2±5.77)msforcontrolgroupand(52.5±6.08)msfor3ppmGansonggroup,P<0.05].InthepresenceofGansong,inhibitionoftheNa+currentwasenhancedbyincreasingfrequencyofdepolarizingpulsefrom56.5msto16ms.Inthecontrolgroup,thetimecourseofrecoveryshowedthatrecoverystartedat19.5msandfinishedby36.5ms.InthepresenceofGansong,thetimecourseofrecoveryshowedthatrecoverystartedat36.5msandfinishedby56.5ms.Na+currentsrecoveredfromtheuse-dependentblockvaryingwithholdingpotential(holdingpotential-dependent).ConclusionsTheresultssuggestedthatNa+currentsrecoveredfromtheuse-dependentblockcorrelatedwithpersistenttime,holdingpotential.TheGansongvolatileoilhasinhibitiveeffectontheNa+currentrecovery.