简介:1.IntrodnctionThispaperextendsthestudyofthesingularmatrixvariatebetadistributionofrank1[1]tothecaseofageneralrank.Astherelateddistributiontonormalsampling,thematrixvariatebetadistribution(alsocalledthemultivariatebetadistribution)hasbeenstudiedextens...
简介:Aprobabilitydensityfunction(PDF)isderivedofbetadistributionwithbothλ3(skewness)andλ4(kurtosis)asparametersforweaklynonlinearwavesurfaceelevationbyuseofamethodrecentlyproposedbySrokosz.ThisPDFnotonlyhasasimplerformthanthewell-knownGram-CharlierSeriesPDFderivedbyLonguet-Higgins,butalsoovercomesanobviousshortcomingofthelatterthatwhentheseriesisunsuitablytruncated,theresultingPDFislocallynegative.TotestthederivedbetaPDF,laboratorialexperimentsofwindwavesareconducted.TheexperimentaldataindicatethatthetheoreticalrequirementsoftheparametersinthebetaPDFarefulfilled.TheexperimentalresultsshowthatthepresentPDFisinbetteragreementwiththemeasureddatathanthebetaPDFonlyincludingparameterλ3,andalsothantheGram-CharlierSeriesPDFtruncateduptothetermofH6.
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简介:AbstractThalassemia, classified as the main types α- and β-thalassemia, is a single gene disorder resulting from globin chain synthesis impairment through the mutation or deletion of globin genes. The incidence of thalassemia is high worldwide, with high associated mortality. Therefore, treatment is important to improve patient outcomes. This paper reviews the current status of β-thalassemia major in China, including its epidemiology and treatment.
简介:目的研究无尿持续非卧床腹膜透析(CAPD)患者腹膜转运功能对骨矿物质代谢的影响。方法选择159例无尿CAPD患者,根据腹膜平衡试验将患者分为2组:低转运特性组87例,高转运特性组72例。检测两组患者血钙、血磷、甲状旁腺激素等生化指标,测定腹膜尿素清除指数(KT/V)及肌酐清除率(CCr)。结果与低转运特性患者相比,高转运特性患者血钙、血磷和甲状旁腺激素水平明显偏低,而KT/V、CCr偏高,差异有统计学意义(P〈0.05)。多元逐步回归分析显示,CCr与血钙、血磷呈负相关(P〈0.05),Kt/V与血钙呈负相关关系(P〈0.05),而D/Pcr与血钙、血磷、甲状旁腺激素无明显相关性。结论低腹膜转运特性患者易出现高磷血症和高甲状旁腺激素;腹摸转运特性能影响血钙、血磷、甲状旁腺激素水平,但之间未见显著相关性。
简介:[摘要] 目的 回顾分析我院近一年根据桂林市卫健委输血病历检查要求,对输血病历进行更细致的规范和完善,分析输血医学科对输血病历监督效果,以更规范成分血制品应用。方法 选取2021年5月我院进行输血治疗的215位患者病例资料604人次输血记录,对比实行一年后的2021年5月197位患者病例资料520人次输血记录,分析不同血制品输血病历质量改善效果,依据国家相关规定进行统计分析。结果 我院输血病历整体质量有大幅提高和改善,其中红细胞制品完善度相对较高,其次是血浆和血小板制品。结论输血病历质量整体完成情况较理想,达到预期效果,但依然有较多提升空间,以后可从多种途径使用多种方法进行加强和完善。
简介:ObjectivesToinvestigatetheeffectsoftestosteroneenanthate(TE)onserumlipidsandlipoproteinsmetabolismandtheexpressionofandrogenreceptor(AR),estrogenreceptorbeta(ER-β)andplateletderivedgrowthfactorbeta(PDGFR-β)inaorticvascularsmoothmuscletissues(VSMTs).MethodsFortyagedmaleratswererandomlydividedinto4groups,groupA(placebogroup),groupB(2.5mg/kgintramuscularinjectionofTEonceaweek),groupC(5.0mg/kgintramuscularinjectionofTEonceaweek),groupD(10.0mg,/kgintramuscularinjectionofTEonceaweek).Allanimalswerefedfreelyduring16-weektreatmentperiods.TheexpressionofAR,ER-βandPDGFR-βwerestudiedbyWesternbolt.ResultsAverageserumLDL-CwasloweringroupDthanthatingroupA(p<0.01).Comparedwiththeothergroups,averageserumTCwasalsoloweringroupD(p<0.05).ARexpressioninaorticvascularsmoothmuscletissuescouldberegulatedbyTE:99.50±21.74,125.38±28.68and101.98±15.42forTEconcentrationsat2.5mg/kg,5.0mg/kgand10.0mg/kg,respectively,theexpressionofER-βcouldberegulatedbyTE:92.34±18.68,47.72±18.12,82.13±23.50,andtheexpressionofPDGFR-βcouldberegulatedaswellbyTE:219.70±45.59,50.16±9.72,125.36±15.74(DataforAR,ER-βandPDGFR-βproteinbandintensitywereexpressedwithx±s,withcontrolgrouptakenas100).ConclusionsThisstudyindicatesthatandrogenshavesignificanteffectsonserumlipidsandlipoproteinmetabolism.Testosteroneenanthateat5.0mg/kgcanstimulatetheexpressionofAR,butinhibitetheexpressionofPDGFR.Testosteroneenanthateattheconcentrationsof5.0mg/kgand10.0mg/kgcaninhibitetheexpressionofER-β.
简介:【摘要】目的:分析末梢血与静脉血在血常规检验中的临床价值。方法:选取我院2019年1月到2020年1月进行体检并接受血常规检验的受检者80例作为研究样本,随机分为对照组和实验组两组,每组受检者各40例。对照组受检者采取末梢血进行血常规检验,实验组采取静脉血进行血常规检验,把两组受检者检验结果进行比较。结果:和对照组相比,实验组受检者Hb、WBC等检验指标较低,组间数据对比显示(P﹤0.05),说明数据差异具备统计学意义;实验组PLT、RBC指标明显高优于对照组(P﹤0.05),两组数据对比发现具备统计学差异。结论:静脉血在血常规检验中优势多于末梢血,可明显提升检测的精确性,且可多次检验,具备推广和使用价值。
简介:Inthepresentpaper,weproposetheqanalogueofSza′sz-Beta-Stancuoperators.Byestimatethemoments,weestablishdirectresultsintermsofthemodulusofsmoothness.Investigatetherateofpoint-wiseconvergenceandweightedapproximationpropertiesoftheqoperators.Voronovskajatypetheoremisalsoobtained.Ourresultsgeneralizeandsupplementsomeconvergenceresultsoftheq-Sza′sz-Betaoperators,thustheyimprovetheexistingresults.