简介：

简介：

简介：

简介：

简介：Infantileaphasia,frequentlyseenofterin-fantileencephalopathysuchasbraintraumaandmeningitis,belongstothecategoriesof"suddenlossofvoice"and"difficultyinspeechduetore-tractionofthetongue"inTCM.Asthereisnoeffectivespecifictherapyintreatingthisdis-easeinmodernmedicine,acupunctureissuperi-ortoothertherapiesinthetreatmentofinfantileaphasia.Inourclinicfordifficultdisease,wehavetreatedtheillnessbyacupuncturewithfili-formandmagneto-plum-blossomneedlecom-binedwithChineseherbsandtutorialmethods.Ourtherapyiseffectiveandquickinproducingtherapeuticeffectswithshorttreatmentcourse,whichisreportedindetailinthefollowing:

简介：

简介：A70-year-oldmanisseenforevaluationofaheartmurmurheardbyhisprimarycareprovider.Thepatientplaysdoublestennistwiceperweekandclaimstobeasymptomatic.–Medication:amlodipineforhypertension.–Physicalexamination(PE):pulse82bpm;bloodpressure140/90mmHg.–Neck:neckveinsflat.Carotidsdelayed.–Chest:clear.–Cardiovascular:grade2/6latepeakingsystolicejectionmurmur.–Extremities:normalpulses.–Echocardiogram:heavilycalcifiedaorticvalve.Peakjetvelocity4.6m/s.Aorticvalvearea0.7cm2.Rightventricularsystolicpressurenotobtainable.

简介：AbstractImportance:Pediatric hypervascular primary airway tumors are progressive, fatal lesions with a low incidence, and the disease is often more serious than that in adults.Objective:To evaluate the clinical efficacy and safety of interventional therapeutic bronchoscopy combined with conservative treatment and bronchial arterial embolization in children with primary airway tumors.Methods:We retrospectively analyzed the clinical data of four pediatric patients with hypervascular primary airway tumor between 2017 and 2019 at Beijing Children’s Hospital.Results:Two patients were low-grade bronchial mucoepidermoid carcinoma, one patient was pleomorphic adenoma, and one was bronchial leiomyoma. Interventional therapeutic bronchoscopy combined with bronchial arterial embolization was used for treatment (all four patients received general anesthesia). The tumors were safely resected in all patients via interventional bronchoscopy. There were no severe complications related to the procedures. All patients were followed up for 5-12 months, and one low-grade bronchial mucoepidermoid carcinoma recurred.Interpretation:Interventional therapeutic bronchoscopy combined with bronchial arterial embolization appears to be a safe and efficient therapeutic method associated with less trauma and fewer complications, including no serious adverse events, in children with hypervascular primary airway tumors without bronchus wall infiltration.

简介：Severeacutepancreatitis(SAP)cancausesystematicinflammatoryresponsesyndrome(SIRS),whichleadstoinjuryorfailureoftheinternalorgansandsystems.1Amongthem,acuterespiratorydistresssyndrome(ARDS)isasevereorfatalcomplication.Inthisarticle,theearlypreventivetreatmentforSAPcombinedwithlunginjureisstudied.

简介：AbstractPediatric and adult spinal cord injuries (SCI) are distinct entities. Children and adolescents with SCI must suffer from lifelong disabilities, which is a heavy burden on patients, their families and the society. There are differences in Chinese and foreign literature reports on the incidence, injury mechanism and prognosis of SCI in children and adolescents. In addition to traumatic injuries such as car accidents and falls, the proportion of sports injuries is increasing. The most common sports injury is the backbend during dance practice. Compared with adults, children and adolescents are considered to have a greater potential for neurological improvement. The pathogenesis and treatment of pediatric SCI remains unclear. The mainstream view is that the mechanism of nerve damage in pediatric SCI include flexion, hyperextension, longitudinal distraction and ischemia. We also discuss the advantages and disadvantages of drugs such as methylprednisolone in the treatment of pediatric SCI and the indications and timing of surgery. In addition, the complications of pediatric SCI are also worthy of attention. New imaging techniques such as diffusion tensor imaging and diffusion tensor tractography may be used for diagnosis and assessment of prognosis. This article reviews the epidemiology, pathogenesis, imaging, clinical characteristics, treatment and complications of SCI in children and adolescents. Although current treatment cannot completely restore neurological function, patient quality of life can be enhanced. Continued developments and advances in the research of SCI may eventually provide a cure for children and adolescents with this kind of injury.

简介：Objective:Toobservethetherapeuticeffectofcombinedtreatmentofdiabetesmellitus(DM)anditscomplications.Methods:30casesofnoninsulindependentdiabetesweretreatedbyelectroacupuncture(EA)ofTianzhu(天柱BL10),Dashu(大杼BL11),Fengmen(风门BL12),Jueyinshu(厥阴俞BL14),etc,massageattheacupointsalongtheBladderMeridian,pointinjectionofVitaminB1,B6,B12pluslidocaineatNeiguan(内关PC6)andSanyinjiao(三阴交SP6,onceevery3days),cuppingandphysiotherapycomprehensively.Thetherapeuticeffectwasanalyzedafter40treatments.Results:Aftertreatment,ofthe30cases,23(76.7%)experiencedremarkableimprovementintheirsymptomsandtherest7(23.3%)hadimprovement,withthetotaleffectiveratebeing100%.Conclusion:TheabovementionedcombinedtreatmentmethodworkswellinimprovingclinicalsymptomsoftypeⅡDMpatients.

简介：Objective:　Toobservethechangesofevokedpotentialsafterseverebraininjuryandtheeffectofmildhypothermiaonacuteseverebraininjury.　　Methods:　Atotalof44patientswithsevereclosedheadinjury(GCS3-8,admittedwithin10hoursfrominjury)admittedfromMay1998toMarch1999wereselectedforthisstudy.Allpatientswereadmittedintotheintensivecareunitanddividedinto2groups,GroupA(GCS3-5)andGroupB(GCS6-8).Patientswerealsorandomlyassignedtoeithernormothermiaorhypothermiasubgroups.Patientsinthehypothermiagroupwerecooledto32-34℃.Mediannerveshort-latencysomatosensoryevokedpotentials(SLSEP)andbrainstemauditoryevokedpotentials(BAEP)wererecordedbeforecoolingand4,24,48,72,96and120hours,respectivelyaftercoolingandtemperatureresuming.SLSEPandBAEPweremeasuredatthesametimeinthenormothermiagroup(controlgroup).Thechangesofevokedpotentials(EP)wereanalyzedbystatisticalmethods.　　Results:　IntheGroupB,N20amplitudesinSLSEPandI/VamplitudesinBAEPaftermildhypothermiatreatmentinthehypothermiagroupdifferedsignificantlyfromthoseinthecontrolgroup(P<0.05).However,intheGroupA,nosignificantdifferenceinallparameterswasfound.　　Conclusions:　Theseresultsdemonstratethatmildhypothermiatreatment(32-34℃)intheGroupBhasasignificantneuroelectrophysiologicaleffectonseverebraininjury.Nevertheless,theeffectofmildhypothermiaintheGroupAisnotapparentandneedsfurtherstudying.

简介：Mentalretardation(MR)childrenarereferredtothosewhohavealowerintelligenceincomparisonwiththatofthenormalchildrenwithsimilaragesinthedevelopmenalstageandsomeconcurrentdefectsinadaptivebehaviorsimultaneously.Inthepastmorethan10years,we

简介：AbstractImportance:Cochlear implantation (CI) is an effective therapy for patients with severe to profound sensorineural hearing loss. It remains controversial whether children younger than 12 months of age should undergo CI.Objective:To evaluate the safety and effectiveness of CI in children younger than 12 months of age.Methods:We performed a retrospective study of clinical data of pediatric patients younger than 12 months of age who underwent CI and were followed up for 1 to 2 years. Patients’ developmental levels were evaluated by the Gesell score before CI. Intraoperative and postoperative complications were recorded to evaluate the safety of CI. Auditory and speech abilities were scored by the LittlEARS® auditory questionnaire (LEAQ), categories of auditory performance (CAP), speech intelligibility rating (SIR), infant-toddler meaningful auditory integration scale (IT-MAIS), and meaningful use of speech scale (MUSS) at 1, 2, 3, 6, 9, and 12 months after CI. The associations between clinical characteristics before CI and postoperative scores at 1 year after CI were analyzed by the linear mixed-effects model.Results:Eighty-nine children (47 boys and 42 girls) were included in this study (mean age at CI, 9.2 ± 1.6 months). Sixteen patients were diagnosed with cochlear malformation and 16 underwent bilateral CI. No severe complications occurred in any patients. The mean developmental quotient of the Gesell score was 78.00 ± 10.03. The median LEAQ scores were 0, 5, 10, 16, 22, 26 and 30 before and at 1, 2, 3, 6, 9, and 12 months after CI, respectively. These findings implied that the LEAQ score greatly improved in the first year after CI. The overall CAP, SIR, IT-MAIS, and MUSS scores also increased with increasing duration after CI. No significant associations were detected between clinical characteristics (age, sex, implant number, pre-CI Gesell score, and inner ear malformation) and LEAQ outcomes at 12 months after CI.Interpretation:With increasing duration after CI, auditory and speech behavior dramatically improve in young children. Our findings indicate that CI is feasible for children younger than 12 months of age.

简介：Objective:Totrytogiveanobjectiveevaluationontheclinicalresearchsituationaboutacupuncturetreatmentoffacialparalysisinthepast50yearsandtrytoprovideapossibleevidenceforclinicalpractice.Methods:Allpapersaresearchedandassessedaccordingtotheinternationalstandardsandclinicalepidemiology.Results:Thereisnosystematicreview(SR)onacupuncturetreatmentoffacialpalsyinatotalof1021articlesenlistedinthepresentpaper.Comparingwiththequantityofthedescriptivestudiesandexpertopinions(constituting84.84%),thatoftherandomizedcontrolledtrials(RCTs)andclinicalcontrolledtrials(CCTs)issmaller(constituting15.16%),be-sides,thequalityofRCTsandCCTsisunsatisfactory.Conclusion:Atpresent,thequantityandqualityofstudieswithRCTsaboutacupuncturetreatmentoffacialparalysiscan'tmeettheneedofclinicalpractice,andinordertoimprovethetherapeuticeffect,ahigherqualityofRCTsandSRisrequired.

简介：

简介：BackgroundHospital-acquiredpneumonia(HAP)isthemostcommonandmostseriousnosocomialinfectionforcardiacsurgerypatients,withhighincidenceandfatalityrate1.ItisimportantforcardiacsurgeonstocorrectlyidentifyHAP,assesstheseverity,andthenadjustanti-infectionmethod,whichcanreducethemortalityrate,shortenhospitalizationtime,andreducethewasteofmedicalresources.ThepurposeofthisresearchistoevaluatetheapplicationvalueoflungCTindiagnosisandtreatmentofHAPaftercardiacsurgery.MethodsAretrospectiveanalysiswasconductedforclinicaldataabout76cardiacsurgerypatientswhowerediagnosedwithHAPduringJanuarytoDecember2013.Theclinicaldatamainlyincludedsymptoms,physicalsigns,laboratoryexaminations(suchasroutinebloodtestsandserumprocalcitonin),andlungCTandX-raydata.OurfocusisonthecomparisonbetweenlungCTandX-raydata.ResultsThepositivediagnosticrate,falsenegativerate,andfalsepositiverateoflungCTwere71/76(93.4%),5/76(6.6%),and1/76(1.3%)respectively.ThecoincidencerateofX-rayandCTwas45/76(59.2%),andthefalsenegativerateofX-raywas23/76(30.3%).ConclusionLungCTisbetterthanX-rayindiagnosisofHAPaftercardiacsurgeryandassessmentofseverity,andhasgreatersignificanceforguidingtherationaluseofantibiotics.Therefore,lungCTisworthyofapplicationandpopularization.

简介：

简介：无

简介：BACKGROUND:Traditionalsubhibernationtherapymayeasilycausecomplications,suchasrespiratorydepressionandhyportensionbecauseofapplicationofchlorpromazinehydrochlorideandpromethazineinalargedosage.OBJECTIVE:Toobservetherapeuticeffectofmodifiedsubhibernationtherapy(alterativeapplicationoffiveanticonvulsantsaccordingtothehalflife)onstatusepilepticusinchildrenwithsevereviralencephalitis(VE).DESIGN:Contrastobservation.SETTING:DepartmentofPediatrics,theFirstHospitalofJilinUniversity.PARTICIPANTS:Theparticipantsinpresentstudywere96patientswithsevereviralencephalitisincluding52boysand44girlswhoreceivedtreatmentintheDepartmentofPediatrics,theFirstHospitalofJilinUniversityfromFebruary2000toMarch2006.AllchildrenmetthediagnosticcriteriaofZhufutongPracticePediatrics(theseventhedition).Twoweeksago,theyevergotupperrespiratoryinfectionorenteronitisandsoonbeforetheonset,spiritabnormal,behaviordisorder,limbsactdisorder,vomit,headache,convulsion,nervoussystemmasculinesignssuchaslimbsactdisord,autonomicnervedamagemanifestation,brainnervepalsy,dysreflexia,meningealirritationsign,cerebrospinalfluidandelectroencephalography(EEG)abnormity.Allparentsprovidedtheconfirmedconsent.Thepatientswererandomlydividedintocontrolgroup(n=40)andexperimentalgroup(n=56).METHODS:Patientsinthecontrolgroupreceivedanticonvulsion,icecompressandroutinetreatment.Theconvulsionwastreatedwithfivedrugs:0.5mg/kgwinterminandphenergan,respectively,100g/Lchlorpromazinehydrochloride(0.5mL/kg),5mg/kgluminal,0.3mg/kgansiolin.Whenconvulsionattacked,thosefivedrugsweregivenalternatively;however,thosewerenotgiveniftheconvulsiondidnotattack.Childrenintheexperimentalgroupweretreatedwithimprovedsubhibernationtherapybasedonroutinetreatment.Thedosagesofanticonvulsantswereasthesameasthoseinthecontrolgroup.Bas