简介:目的:探讨病毒性心肌炎(VM)患者血清CBV-lgM抗体与左室总射血分值(EF)值及峰射血率(PER)、峰充血率(PFR)的关系,以及心肌显像与心肌各局部EF值的关系.方法:对120例心肌炎患者以ELISA法测CBV-lgM抗体,用99mTc-MIBI心肌显像对其中37例行核素心室造影,测左室总体EF值及局部EF值,并测其PER和PFR;设正常对照40例.结果:(1)CBV-lgM抗体阳性者120例中有VM85例(70.83%),对照组仅2例(5%),P<0.01;(2)99mTc-MIBI心肌断层显像异常120例中有VM105例(87.5%),对照组仅1例(2.5%),P<0.01;(3)CBV-lgM抗体阳性与99mTc-MIBI心肌显像VM异常符合率为78.95%;(4)CBV-lgM抗体阳性中37例核素心室造影测得左室总EF降低者21例(56.7%);(5)节段性EF值降低33例(89.19%);(6)PER、PFR降低20例(54.05%);(7)心肌显像异常与EF降低符合率89.19%;(8)37例核素心室造影测定:PER降低22例(59.46%),PFR降低21例(56.75%);(9)各节段EF降低者:侧壁(LAT)l2例(33.43%),下壁(INF)15例(40.54%),心尖部(AP)12例(33.43%),下间隔(IN-SEP)24例(64.86%),室间隔(SEP)31例(83.78%).结论:病毒性心肌炎患者血清CBV-lgM抗体水平与心肌显像和心功能有良好的相关性,有助于该病的诊断和预后判断.
简介:UsingaregionalclimatemodelMM5nestedtoanatmosphericglobalclimatemodelCCM3,aseriesofsimulationsandsensitivityexperimentshavebeenperformedtoinvestigatetherelativeLastGlacialMaximum(LGM)climateresponsetodifferentmechanismsoverChina.Modelsimulationsofthepresentday(PD)climateandtheLGMclimatechangeareingoodagreementwiththeobservationdataandgeologicalrecords,especiallyinthesimulationofprecipitationchange.UnderthePDandLGMclimate,changesofearthorbitalparametershaveasmallinfluenceontheannualmeantemperatureoverChina.However,themagnitudeoftheeffectshowsaseasonalpattern,withasignificantresponseinwinter.Thus,thisinfluencecannotbeneglected.DuringtheLGM,CO_2concentrationreacheditslowestpointto200ppmv.ThisresultsinatemperaturedecreaseoverChina.TheinfluencesofCO_2concentrationonclimateshowseasonalandregionalpatternsaswell,withasignificantinfluenceinwinter.Onthecontrary,CO_2concentrationhaslessimpactinsummerseason.Insomecases,temperatureevenincreaseswithdecreasinginCO_2concentration.Thistemperatureincreaseistheoutcomeofdecreaseincloudamount;henceincreasethesolarradiationthatreachedtheearth'ssurface.Thisresultsuggeststhatcloudamountplaysaveryimportantroleinclimatechangeandcoulddirecttheresponsepatternsofsomeclimatevariablessuchastemperatureduringcertainperiodsandovercertainregions.IntheTibetanPlateau,thetemperatureresponsestochangesoftheabovetwofactorsaregenerallyweakerthanthoseinotherregionsbecausethecloudamountinthisareaisgenerallymorethanintheotherareas.Relativetothecurrentclimate,changesinorbitalparametershavelessimpactontheLGMclimatethanchangesinCO_2concentration.However,bothfactorshaveratherlesscontributionstotheclimatechangeintheLGM.About3%-10%changesintheannualmeantemperaturearecontributedbyCO_2.
简介:UsingaregionalclimatemodelMM5nestedtoanatmosphericglobalclimatemodelCCM3,aseriesofsimulationsandsensitivityexperimentshavebeenperformedtoinvestigatetherelativeLGMclimateresponsetochangesofland-seadistribution,vegetation,andlarge-scalecirculationbackgroundoverChina.Modelresultsshowthatcomparedwiththepresentclimate,thefluctuationsofsea-landdistributionineasternAsiaduringtheLGMresultinthetemperaturedecreaseinwinterandincreaseinsummer.IthassignificantimpactonthetemperatureandprecipitationintheeastcoastalregionofChina.TheimpactonprecipitationintheeastcoastalregionofChinaisthemostsignificantone,with25%-50%decreaseinthetotalprecipitationchangeduringtheLGM.Ontheotherhand,thechangesinsea-landdistributionhavelessinfluenceontheclimateofinlandandwesternpartofChina.DuringtheLGM,significantchangesinvegetationresultintemperaturealternatingwithwinterincreaseandsummerdecrease,butdifferencesintheannualmeantemperatureareminor.DuringtheLGM,theglobalclimate,i.e.,thelarge-scalecirculationbackgroundhaschangedsignificantly.ThesechangeshavesignificantinfluencesontemperatureandprecipitationoverChina.Theyresultinconsiderabletemperaturedecreasesinthisarea,anddirecttheprimarypatternsandcharacteristicsoftemperaturechanges.Resultsdisplaythat,northeasternChinahasthegreatesttemperaturedecrease,andthetemperaturedecreaseintheTibetanPlateauislargerthanintheeasternpartofChinalocatedatthesamelatitude.Moreover,thechangeoflarge-scalecirculationbackgroundalsocontrolsthepatternofprecipitationchange.Resultsalsoshowthat,mostofthechangesinprecipitationoverwesternandnortheasternpartsofChinaaretheconsequencesofchanginglarge-scalecirculationbackground,ofwhich50%-75%ofprecipitationchangesovernorthernandeasternChinaaretheresultsofchangesinlarge-scalecirculationbackground.OverChina,theLGM
简介:【摘要】目的:探讨在呼吸道感染(RTI)诊断中检测呼吸道(RT)病原体血清免疫球蛋白M(lgM)抗体的应用价值。方法:抽取拟诊100例RTI病例,患者均于2022.01~2022.05期间就诊。所有对象均检测RT病原体血清lgM抗体,常见病原体包括9种,以间接免疫荧光法完成检测。结果:经检测RT病原体,本组100例患者中共检出35例单项阳性,检出率35.0%,其中位列前三的病原体为副流感病毒(PIV)5例(5.0%),乙型流感病毒(IVB)12例(12.0%),肺炎支原体(MP)16例(16.0%)。检出合并2种感病原体染者10例,无3种、4种混合感染。结论:在RTI诊断中检测7种RT病原体血清lgM抗体可对具体感染病原体类型进一步明确,以科学指导临床治疗和用药,可推广借鉴。
简介:摘要目的对血清免疫球蛋白IgM和C反应蛋白(CRP)联合测定对新生儿早期感染性疾病的临床意义进行研究分析。方法我院收治100例发生细菌感染的新生儿为治疗组,50例正常足月新生儿为对照组,对治疗组与对照组的血清IgM和CRP水平使用散射比浊法进行测定。结果治疗组的IgM和CRP值分别为0.43±0.19g/L、46.21±26.01mg/L,对照组的IgM和CRP值分别为0.20±0.06g/L、1.02±0.29mg/L;两组数值相比均具有显著差异(P<0.05)。结论血清IgM和CRP联合测定能够作为诊断新生儿早期细菌感染的指标。