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简介：APRIL2015ChinaPledgesEducation,Hospital,JurorSystemReformsOnApr.1,China’scentralauthoritiesrolledoutplanstosupportruralteachers,overhaulpublichospitalsandimprovepublicsupervisionofcourtcases.Theplanswereadoptedatthe11thmeetingofthecentralleadinggroupfordeepeningoverallreformonWednesday,duringwhichPresidentXiJinping,whoisalso

简介：下面的这个故事有点不靠谱，里面隐含着知识性错误，每找到一处便可得到一枚智慧币。

简介：BeijinghasbeenoneoftheepicentersattackedmostseverelybytheSARS-CoV(severeacuterespiratorysyndrome-associatedcoronavirus)sincethefirstpatientwasdiagnosedinoneofthecity'shospitals.WenowreportcompletegenomesequencesoftheBJGroup,includingfourisolates(IsolatesBJ01,BJ02,BJ03,andBJ04)oftheSARS-CoV.ItisremarkablethatallmembersoftheBJGroupshareacommonhaplotype,consistingofsevenlocithatdifferentiatethegroupfromotherisolatespublishedtodate.Among42substitutionsuniquelyidentifledfromtheBJgroup,32arenon-synonymouschangesattheaminoacidlevel.Rootedphylogenetictrees,proposedonthebasisofhaplotypesandothersequencevariationsofSARS-CoVisolatesfromCanada,USA,Singapore,andChina,gaverisetodifferentparadigmsbutpositionedtheBJGroup,togetherwiththenewlydiscoveredGD01(GD-Ins29)inthesameclade,followedbytheH-UGroup(fromHongKongtoUSA)andtheH-TGroup(fromHongKongtoToronto),leavingtheSPGroup(Singapore)moredistant.ThisresultappearstosuggestapossibletransmissionpathfromGuangdongtoBeijing/HongKong,thentoothercountriesandregions.

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简介：TheR(replicase)proteinistheuniquelydefinednon-structuralprotein(NSP)responsibleforRNAreplication,mutationrateorfidelity,regulationoftranscrip-tionincoronavirusesandmanyotherssRNAviruses.Basedonourcompletegenomesequencesoffourisolates(BJ01-BJ04)ofSARS-CoVfromBeijing,China,weanalyzedthestructureandpredictedfunctionsoftheRproteinincomparisonwith13otherisolatesofSARS-CoVand6othercoronaviruses.TheentireORF(open-readingframe)encodesfortwomajorenzymeactivities,RNA-dependentRNApolymerase(RdRp)andproteinaseactivities.TheRpolyproteinunder-goesacomplexproteolyticprocesstoproduce15function-relatedpeptides.Ahydrophobicdomain(HOD)andahydrophilicdomain(HID)arenewlyidentifiedwithinNSP1.ThesubstitutionrateoftheRproteinisclosetotheaverageoftheSARS-CoVgenome.ThefunctionaldomainsinallNSPsoftheRproteingivedifferentphylogeneticresultsthatsuggesttheirdifferentmutationrateunderselectivepressure.ElevenhighlyconservedregionsinRdRpandtwelvecleavagesitesby3CLP(chymotrypsin-likeprotein)havebeenidentifiedaspotentialdrugtargets.Findingssuggestthatitispossibletoobtaininformationaboutthephy-logenyofSARS-CoV,aswellaspotentialtoolsfordrugdesign,genotypinganddiagnosticsofSARS.

简介：TheSixthEuropeanCommission(EC)andinternationalconferenceon‘Themanagementanddisposalofradioactivewaste':Euradwaste'04,washeldon29-31March2004inLuxembourg.

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简介：推出2004歙的蒙迪欧是长安福特在岁末年初之即做出了两大举动之一。

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简介：一直被誉为专业越野车品牌的江铃陆风，也借助年初新车层出不穷的风朝，推出了04款江铃陆风。

简介：第一，项目划分，以现行全统定额、行业定额、地方定额为基础，与《建设工程工程量清单计价规范》GB50500-2013（以下简称2013版《清单计价规范》）的章、节顺序相衔接。切实反映新技术、新工艺、新材料、新设备变化情况，调整不合理项目，删除技术淘汰项目，增加建筑节能、环保等项目。

简介：近年来,集成电路类电子产品走私活动频繁,对我国电子市场健康发展带来一定的影响,国务院领导对此专门作出批示。为此,根据海关总署2016年打私工作部署,海关总署缉私局将打击电子产品走私列为'国门利剑2016'联合专项行动的重点任务,部署重兵、重拳出击,开展打击整治。

简介：WesummarisetheHEPVis'01workshopheldinMay2001atNortheasternUniversity,Boston.Generalissuessuchasarchitectureanddesignoftheframeworksandtoolkitsaredescribedaswellasthestatusofawiderangeofgenericanalysisandvisualisationtoolsandexperiment-specificsystems.

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