学科分类
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371 个结果
  • 简介:Theworldisexperiencingagingofitspopulation.Age-specificincidenceratesofcancerarehigherandcancerisnowrecognizedasapartofaging.Treatingolderpatientscanbechallenging.Theclinicalbehaviorofsometumorschangeswithageandtheagingprocessitselfbringsphysiologicalchangesleadingtodeclineinthefunctionoforgans.Itisessentialtoidentifythosepatientswithlongerlifeexpectancy,potentiallymorelikelytobenefitfromaggressivetreatmentvs.thosethataremorevulnerabletoadverseoutcomes.Aprimarydeterminationwhenconsideringtherapyforanoldercancerpatientisapatient'sphysiologic,ratherthanchronologicage.Inordertodifferentiateamongstpatientsofthesameage,itisusefultodetermineifapatientisfitorfrail.Frailolderadultshavemultiplechronicconditionsanddifficultiesmaintainingindependence.Theymaybemorevulnerabletotherapytoxicities,andmaynothavesubstantiallastingbenefitsfromtherapy.Geriatricassessment(GA)maybeusedasatooltodeterminereversibledeficitsanddevisetreatmentstrategiestomitigatesuchdeficits.GAisalsousedintreatmentdecisionmakingbyclinicians,helpingtoriskstratifypatientspriortopotentiallyhigh-risktherapy.AnimportantpracticalaspectofGAisthefeasibilityofincorporatingitintoabusyoncologypractice.KeyconsiderationsinperformingtheGAinclude:availableresources,patientpopulation,GAtoolstouse,andwhowillberesponsibleforusingtheGAresultsanddevelopcareplans.ChallengesinimplementingGAinclinicalpracticewillbediscussed.

  • 标签: 临床医生 健康评估 肿瘤 癌症患者 遗传算法 生理变化
  • 简介:Amomentactuatorwithdirectdetectionofforcesisdescribed,Momentfrequencyre-sponseandmomentexcitationpurityasperformancecriteriaareproposed.Methodsfortheperfor-mancecalibrationoftheactuatorarepresented.Assessmentiscarriedoutbymeansofthereciprocityprinciple.

  • 标签: MOMENT ACTUATOR PERFORMANCE CALIBRATION RECIPROCITY
  • 简介:Byexpandingtheperturbationofcovariancematrixinthepowersofer-rorterm,theinfluencefunctionsforfivecanonicalmeasurementsinCCAaredevel-opedandthreesampleversionsaregiven.Forgeneralizedcorrelationcoefficientp_z,theinfluencefunctionisaquadraticformofr.v.z,anditsdistributionisconsidered.ApracticalexampleiUustratestheutilityoftheproposedinfluencefunctions.

  • 标签: CANONICAL CORRELATION analysis perturbation/influence FUNCTION influential
  • 简介:Apracticalmethodforvisualizingfloodareaandevaluatingdamageispresented,whichconsistsoftwotechnicalapproaches:self-programmingandadaptingcommercialGISplatforms.Thelow-costandeasy-to-useGIS-Basedmodeldevelopedbyself-programmingcanmeetcurrentrequirementsofmostlocalauthorities,especiallyindevelopingcountries.Inthismodel,twocases,non-sourcefloodandsourceflood,aredistinguishedandtheSeed-spreadalgorithmsuitableforsource-floodisdiscussed;Theflooddamageisassessedbyoverlayingthefloodarearangewiththematicmapsandotherrelatedsocialandeconomicdata.andallthematicmapsareconvertedtorasterformatbeforeoverlayanalysis.Twomeasuresaretakentoimprovetheoperationefficiencyofspeedseed-spreadalgorithm.TheaccuracyofthemodelmainlydependsontheresolutionandprecisionoftheDEMdata,andtheaccuracyofregisteringallrasterlayersandthequalityofattributedata.

  • 标签: 水灾地区 灾害评估 “seed SPREAD algorithm” 种子传播算法
  • 简介:Although2013couldbecharacterizedasanormalyear,theinternationalstrategicsituationhasundergonesomeprofoundchanges.OneofthemostimportantisthattheUnitedStatesmayhavequietlygivenupitsroleofthe"worldpolice."ChinamustconsiderthepossibilityoftheU.S.retreatingfromitscurrentpositionoftheworld’ssolesuperpowerand"worldpolice",andbewellpreparedtocopewiththepossibleeffectsaccordingly.

  • 标签: 国际关系 国际问题 世界和平 国际战略形势