简介：ObjectivesToevaluatetheeffectivenessoffirebirdstentforthetreatmentofcoronarydenovolesioncomparedwithcypherstent.MethodsNinety-oneconsecutivepatientswith156lesionswhounderwentcoronarycypher(n=68lesions)andfirebird(n=88lesions)implantation,quantitativecoronaryangiography(QCA)wasperformedatthetimeofstentimplantationandsubsequentlyat8monthspost-stenting.Smallvesseldiseasewasdefinedas≤2.5mmofreferencevesseldiametermeasuredbyQCA.Majoradversecardiacevents(MACE)includingdeath,thrombosis,nonfatalmyocardialinfarctionandtargetlesionrevascularization(TLR)werecomparedbetweenthetwogroups.ResultsBaselineclinicalcharacteristicsandangiographicparametersweresimilarbetweenthetwogroups.Seven-monthangiographicfollow-up,thelatelosswasnotdifferentbetweenthetwogroups(0.14±0.38mmvs0.13±0.17mm,P>0.05).Similarly,overallthrombosisrateweresimilarinbothgroups(1.5%vs1.1%,P>0.05).However,in-stentrestenosisaswellasin-segmentrestenosisrateweresignificantlyhigherincyphergroupthanthatinfirebirdgroup(4.4%vs0%and19.1%vs3.4%,P=0.047andP=0.001respectively).TLRwasalsohigherinthecyphergroup(10.3%vs2.3%,P=0.033)comparedwithfirebirdgroup.ConclusionsInthissmallsamplesize,non-randomizedstudy,thedataindicatedthatimplantationoffirebirdstentforthetreatmentofsmallcoronarylesionshowedmorefavorableresultsinrespectiveofrestenosiscomparedwithcypherstentimplantation.Amulti-center,large-samplesize,randomizedstudy,therefore,maybewarranted.