简介:Riverswithheterogeneousbedsedimentstypicallyshowasystematicdownstreamvariationincharacteristicgrainsizewhensubjectedtoaggradationordegradation.Recentlytheauthorsreportedonadecouplednumericalmodelbasedontheassumptionofnonuniformflowwhichreproducedtheresultsofasetofexperimentsongrainsorting.Thesameexperimentscanalsobereproducedusinganumericalmodelforwhichmuchoftheflowdomainisapproximatedasquasinormal.Thekeytothissimplificationistheuseofshockfittingtolocatethedownstreamfrontofgravelaggradation.Oncetheshockha?
简介:Thispaperinvestigatestheeffectofupstreamwakeonunsteadyseparatedflowfieldofdownstreamadjacentvanesbysolving2DunsteadyReynolds-averagedNavier-Stokesequationsdiscretizedbyahigh-orderscheme.Theresultsindicatedthatthemaximumrelativereductionoflosscoefficientwas27.2%whentherelativepassingfrequency(theratioofwakepassingfrequencytothecharacteristicfrequencyoftrailing-vortexsheddingofdownstreamadjacentrotor)islessthan2.5.Theamplitudeofwakedefectexistsathresholdvalueandtheaerodynamicperformanceisenhancedmonotonicallywiththeamplitudeofwakedefectbasically.Theeffectiverangeofincidencemustbegreaterthan8°,whichisnearthestallboundary.
简介:<正>Usingsubtractioncloning,weidentifiedthehumanN-MycDownstream-RegulatedGene-2(hNDRG2),locatedat14q11.2,asacandidatetumorsuppressorgene.Semi-quantitativeRT-PCRshowedthattheexpressionofhNDRG2in15of27(56%)humanGBMtissuesandall6humanglioblastomacelllineswassignificantlylowerthanthatinthenormalbrain.TheexpressionofhNDRG2alsowasevaluatedin60lung-carcinomapatients.17of26casesofsquamouscarcinomaand4of11casesofsmallcelllungcancerdisplayed