简介：Objective:Establishnormativedatafortympanicelectrocochleography(TMECochG)parametersinnormalhearingadultswithoutMeniere'sdisease's(MD)symptoms.DescribeTMECochGvariablesthathelptodistinguishnormalfromMDears.Materialandmethods:Weenrolled100subjects(N?200ears),59females,agedbetween19and71yearsfrom09/2010to04/2014.Inclusioncriteria:normalotomicroscopy,hearingthresholds25dBnHLfrom250to4000Hz,normaltympanogram,nosymptomsofMDaccordingtotheAAO-HNS1995criteriaandGibson'sscore<7.Weexcludedsubjectswithdizziness,auralfullnessorothersymptomsofendolymphatichydrops.Thefollowingparameterswereanalyzed:SP/APamplituderatio,SP/AParearatioandthedifferencebetweenAPlatencywithrarefactionandcondensationstimuli.Results:Therewasnosignificantdifferencebetweenrightandleftears(Intraclasscorrelationcoefficient<0.6).SP/APamplituderatiovariedbetween0.084and0.356andSP/AParearatiobetween0.837and1.671(percentiles5and95).TheAPlatencydifferencetorarefactionandcondensationclickswasbetween0.0and0.333ms.Conclusion:NormativedataforTMECochGparameterswereestablishedin100normalhearingsubjectswithoutMD.Thesedatacanbeusedtodistinguishnormalfrompathologicalfindingsandinfollow-upofMDpatients.

简介：AbstractElectrocochleography (ECochG) is an electrophysiological technique that records electrical potentials generated by different components of the inner ear and peripheral cochlear nerve in response to acoustic stimulation. ECochG responses can be analyzed into (1) cochlear microphonics (CM), (2) auditory nerve neurophonics, (3) summating potential, and (4) compound action potential. Over the past few decades, there have been ongoing refinements in technique and updates in the understanding of recorded potentials. Historically, ECochG found its main application in the diagnostic evaluation of Meniere’s disease (MD). However, in the last decade, the focus has shifted towards cochlear implantation (CI). In patients with residual hearing after CI, combined electric and acoustic stimulation has resulted in improved hearing and speech outcomes. Despite efforts to mitigate trauma during electrode insertion, hearing preservation rates vary after surgery. During implantation, real-time ECochG offers an opportunity to measure frequency specific CMs elicited from a localized region in the cochlea as the surgeon inserts the electrode array. In extracochlear ECochG recordings, the recording electrode can be placed on the promontory, the stapes, or the tympanic membrane. Intracochlear ECochG can be performed by inserting a recording electrode into the cochlea or by using one of the CI electrodes as the recording electrode. The loss of intraoperative ECochG signal may indicate cochlear trauma from electrode insertion, but the association between intraoperative ECochG changes and cochlear trauma remains controversial. The ability to monitor cochlear trauma during CI electrode placement holds promise to improve hearing preservation outcomes, modify surgical techniques, and change electrode design. The goal of this review is to provide a comprehensive overview of the electrophysiology and history of ECochG, discuss its recent applications in CI, and explore the ongoing research in this expanding field.