简介：Myhusband,jerry,andIdrovehomeinsilencefromthehospitalthateveninginApril1997.Notthecomfortablesilenceofacouplemarriedmorethan40years,thekindofeasygoingcompanionshipthatneedednowords.No,thesilencethatloomedbetweenuswas

简介：WhenIcameacrossLamaGangcheninNepalyearsago,hewasthenresidinginItaly.HehasagoodcommandofBuddhistTantrictheoryandpractice,aswellaswideknowledgeofTibetanmedicine.HeisalsoactiveinpropagatingTibetanBuddhismandTibetanmedicine,especiallyinworkingtoprotectthepsychicenvironmentandpromoteeducationandcharityundertakings.Forthispurpose,hehasvisitedmorethan30countriesandregions.

简介：Objective:Toevaluatetheeffectofosteoporosisonfracturehealingthroughobservingthehistomorphologicalchanges,bonemineraldensityofcallusandexpressionanddistributionoftransforminggrowthfactorbeta1(TGF-β1),basicfibroblastgrowthfactor(bFGF)andbonemorphogeneticprotein-2(BMP-2)inovariectomizedrats.Methods:SixtyfemaleSprague-Dawleyrats(aged12weeksandweighing235gonaverage)wererandomlydividedintoanovariectomized(OVX)group(n=30)andasham-operated(SO)group(n=30).OvariectomywasperformedintheOVXratsandsameincisionwasmadeintheSOrats.Threemonthslater,fractureoffemoralshaftwasmadeonalltherats.Thentheywerekilledatdifferenttimepoints.Callusformationwasobservedwithhistologicalandimmunohistochemicalmethods.Results:AreductionincallusandbonemineraldensityinthehealingfemurandadecreaseofosteoblastsexpressingTGF-β1nearthebonetrabeculawereobservedintheOVXrats3-4weeksafterfracture.HistomorphologicalanalysisrevealedahighercontentofsoftcallusintheOVXratsthanthatintheSOrats.ImmunohistochemistryresultsshowedthatnoremarkabledifferenceinexpressionanddistributionofBMP-2andbFGFbetweentheOVXandSOgroupswasfound.Conclusions:Osteoporosisinfluencesthequantityandqualityofcallusduringtheearlyperiodoffracturehealing.TheeffectofosteoporosisonfracturehealinghasnorelationshipwiththeexpressionofBMP-2orbFGF.ThedecreasedexpressionofTGF-β1inosteoblastsmaycauseadecreaseinqualityoffacturehealingafterosteoporosis.

简介：IntroductionMeditationhasbeenpracticedover2,600yearsinbothmonasticandsecularsettingsinmanyAsianBuddhistcountries.Thepracticeofmeditationisregardedastheessenceofthepathtoachievetheenlightenment,accordingtoBuddhism,andithasbeendevelopedintoavarietyoflineagesandtraditionsindifferentculturessinceever.

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简介：答案的二种类型(ZnSO<潜水艇class=“a-plus-plus”>4,MgSO<潜水艇class=“a-plus-plus”>4)被选择在愈合的电极淀积上学习矿物质混合的影响具体裂缝的效果。四个参数(ie，重量获得的率，表面涂层，充满深度的裂缝闭合和裂缝)被测量。在裂缝的电沉积的矿物质作文被分析。学习证明有10%苍蝇灰的臼标本的愈合的效果是最糟，当没有苍蝇灰，有20%苍蝇灰的臼标本的愈合的效果比标本的好时。重量获得，表面涂层，充满深度的裂缝闭合和快克的率与增加扎根的成粒的强风炉子炉渣(GGBS)的内容减少。矿物质混合没在沉积物的作文上有影响。

简介：Coverageholesoftenappearinwirelesssensornetworksduetosensorfailureortheinheritanceofsensor'srandomdistribution.Inthehybridmodel,mobilesensorsinthenetworkareacquiredtohealcoverageholesbytheirmobility.Whenmultiplecoverageholesappearinthesensornetworkandeachofthemhasatimerequirement(inwhichthecoverageholehastobehealed),conflictsfortherequestsofthesamemobilesensormayarise.Adistributedmultiplemobilesensorschedulingprotocol(DMS)isproposedinthispapertosolvethisproblembyfindingmobilesensorsinthetimeresponsezonedefinedbythetimerequirementofeachcoveragehole.SimulationresultsshowthatDMScanwellschedulethemobilesensorstomovetomultiplecoverageholeswithinthetimerequirement.

简介：BACKGROUND:Livedeliverylimitstheclinicalapplicationofmaggottherapy.TodateinChina,therearenoinvivoreportsregardingwoundhealingmechanismsofmaggottherapyortheeffectsofmaggothomogenateonwoundnerveregeneration.OBJECTIVE:Toavoidcomplicationsduetotheuseoflivemaggots,anasepticmaggothomogenatewasapplied.SubstanceP(SP)andgeneproteinproduct9.5expressioninacutaneouswoundwasanalyzedtoexplorepossiblemechanismsofneuralregenerationandwoundhealingintherat.DESIGN,TIMEANDSETTING:ArandomgroupingandcontrolledanimalstudywasperformedatthelaboratoryoftheDepartmentofOrthopedicSurgery,FirstAffiliatedHospital,DalianMedicalUniversityfromAugust2008toApril2009.MATERIALS:LivemaggotswereculturedandprovidedbythelaboratoryoftheDepartmentofOrthopedicSurgeryoftheFirstAffiliatedHospital,DalianMedicalUniversity,China.METHODS:Atotalof48adultratswereselectedandtwoacute,full-thicknesswounds(round,1.5cmdiameter)werecreatedonthebackofeachrat.Thetwowoundswererandomlyassignedtohomogenateproductandcontrolgroups.Followingtwo-stepdisinfectionofmaggots,ahomogenatewasproducedfrom10maggotsandappliedtothewoundareainthehomogenateproductgroup,whilethewoundsinthecontrolgroupweretreatedwithnormalsalinealone.MAINOUTCOMEMEASURES:Ondays1,3,7,10,14,and21followinginjury,thewoundtissuewasexcised.HistologicalexaminationofthewoundwasobservedbyhematoxylinandeosinstainingorMasson'sTrichromestaining.SPandproteingeneproduct9.5expressionswereexaminedbyimmunohistochemistrytoevaluatewoundneuralregeneration.RESULTS:Ondays7,10,and14,therateofwoundhealingwassignificantlygreaterinthehomogenateproductgroupcomparedwiththecontrolgroup(P<0.05),andhomogenatehealingwasbetterthanthatseeninthecontrolgroup.Ondays3,7,and10,SPexpressionincellsandregenerativenerveswassignificantlygreaterinthehomogenateproductgroupcomparedw

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简介：BelovedisoneofToniMorrison’smostfamousnovelsandattractsmuchattentionfromthepublic.ThisessayaimstoanalyzethehealingprocessofSethe’straumafromtheperspectiveofpsychologicalanalysis.Therearefourparts.First,itintroducestheplotofthestoryandthetheory.ThesecondpartanalyzestheformingofSethe’straumaandthethirdpartdiscussesthehealingprocess.Thelastpartreachestheconclusion.ByanalyzingSethe’straumafrompsychoanalysis,thispaperaimstohelptheseblackpeopletoreconstructtheiridentityandachieverenascence.

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简介：AIM:Toinvestigatewhetherthesimultaneoustreatmentwithhumangrowthhormone(hGH)abolishesthenegativeeffectsofeverolimusonanastomotichealing.METHODS:Forty-eightmaleSprague-Dawley-ratswererandomizedtothreegroupsof16animalseach(Ⅰ:vehicle;Ⅱ:everolimus3mg/kgpo;Ⅲ:everolimus3mg/kgpo+hGH2.5mg/kgsc).AnimalswerepretreatedwithhGHand/oreverolimusdailyforsevendays.Thenastandardanastomosiswascreatedinthedescendingcolonandtreatmentwascontinuedforanothersevendays.Theanastomosiswasresectedintotoandtheburstingpressurewasassessedasamechanicalparameterofintestinalhealing.Moreover,biochemical(Hydroxyproline,PCNA,MPO,MMP-2andMMP-9)andhistological(celldensity,angiogenesis,amountofgranulationtissue)parametersofintestinalhealingwereassessed.RESULTS:AnastomoticburstingpressurewassignificantlyreducedbyeverolimusandasimultaneoustreatmentwithhGHresultedinconsiderablyhighervalues(Ⅰ:134±19mmHg,Ⅱ:85±25mmHg,Ⅲ:114±25mmHg;P<0.05,ⅠvsⅡ;P=0.09,ⅠvsⅢandⅡvsⅢ)HydroxyprolineconcentrationwassignificantlyincreasedbyhGHcomparedtoeverolimusalone(Ⅰ:14.9±2.5μg/mg,Ⅱ:8.9±3.6μg/mg,Ⅲ:11.9±2.8μg/mg;P<0.05,?ⅠvsⅡ/ⅢandⅡvsⅢ).ThenumberofMPO-positivecellswasreducedsignificantlybyhGHcomparedtoeverolimusalone(Ⅰ:10±1n/mm~2,Ⅱ:15±3n/mm~2,Ⅲ:9±2n/mm~2;P<0.05,ⅠvsⅡandⅡvsⅢ),whilethenumberofPCNA-positivecellswereincreasedbyhGH(Ⅰ:28±3/mm~2,Ⅱ:12±3/mm~2,Ⅲ:26±12/mm~2;P<0.05,?Ⅰ?vsⅡandⅡvsⅢ).Correspondingtothesebiochemicalfindings,HEhistologyrevealedsignificantlyincreasedamountofgranulationtissueinhGH-treatedanimals.CONCLUSION:InhibitionofintestinalwoundhealingbyeverolimusispartiallyneutralizedbysimultaeoustreatmentwithhGH.BothinflammationaswellascollagendepositionisinfluencedbyhGH.

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简介：Angiogenesis在出生后的生命期间在胚胎的脉管的树的发展以及处于几个正常、病理学的条件起一个基本作用。Bloodsupply，由neovascularization建立了，在愈合弯屈期间为histogenesis是必要的以及变长的手足在骨胳的损伤sequalae的治疗广泛地适用。Butlittle注意对这个区域被给予了。这评论试图在机械应力下面总结angiogenesis规定，在愈合的创伤中的angiogenesis的过程和angiogenesis，特别地与紧张压力原则联合。

简介：Toevaluatetheinfluenceofosteoporosisonthemiddleandlateperiodsoffracturehealingprocessthroughobservingthehistomorphologicalchanges,honemineraldensityandbiomechanicalpropertiesinovariectomizedrats.Methods:Eighty-fourfemaleSDratsof4monthsoldwererandomlydividedintoosteoporosisgroupandshamoperationgroup,42ineach.Ratsinosteoporosisgroupwereperformedovariectomyoperationwhilethoseinshamoperationgroupweregivenshamoperation.Amidshafttibiafracturemodelwasestablished10weeksafterovariectomy.Tibiaswereharvested2,4,6,12,18weeksafterfractureforbonemineraldensity,histomorphologicalandbiomechanicalevaluation.Results:Comparedwiththeshamoperationgroup,callusbonemineraldensitywas12.8%,18.0%,17.0%lowerinosteoporosisgroup6,12,18weeksafterfracture,respectively(P<0.05);callusfailureloadwas24.3%,31.5%,26.6%,28.8%lowerinosteoporosisgroup,andcallusfailurestresswas23.9%,33.6%,19.1%,24.9%lowerinosteoporosisgroup4,6,12,18weeksafterfracture,respectively(P<0.05).Inosteoporosisgroup,endochondralboneformationwasdelayed,moreosteoclastcellscouldbeseenaroundthetrabecula,andthenewbonetrabeculaarrangedlooselyandirregularly.Conclusions:Osteoporosisinfluencesthemiddleandlateperiodsoffracturehealingintheratosteoporoticmodel.Theimpairmentisconsideredtobetheresultofcombinedeffectsofprolongedendochondralcalcification,highactivatedosteoclastcellandthedecelerationoftheincreaseinbonemineraldensity.

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简介：Objective:Tostudythechangeofthestressshieldingrateofstress-relaxationplateinvivoanditsinfluenceonfracturehealing.Methods:Thediaphysesofbilateraltibiasin70NewZealandrabbitswereosteotomizedandfixedwithstressrelaxationplates(SRP,theSRPgroup)andrigidplates(RP,theRPgroup),respectively.Thefracturehealingprocessinthese2groupswasinvestigatedbyradiography,lightandpolarizedlightmicroscopyandbiomechanicaltestat2to48weekspostoperatively.Results:Earlyafterfixationthestressshieldingratewasabout70%inbothgroups.WhileintheSRPgroupthestressshieldingratedecreasedgraduallyastimepassed,whyichwassignificantlylowerthanthatoftheRPgroup(P<0.05)bytheendofthe8thpostoperativeweek,andstabilizedatthelevelofabout27%at36-48weeksafterfixation.AbundantexternalcallusassociatedwiththeformationofcartilaginouscalluscouldbeobservedintheSRPgroupat2-4weekspostoperatively.Thetransformationofthecallusintothelamellarbonebeganat8-12weeks,thecollagengraduallyarrangedinorder,andthemechanicalnatureoftheunitedbonewasgraduallystrengthened,too.IntheRPgroup,theexternalcalluswasscarceattheearlystageoffracturehealing,andthecallusremodelingatthelatestageoffracturehealingwasdominatedbyboneabsorption.Theultimatebendingstrength(UBS)wasonly57.95%ofthatofthenormalby48weeks.Conclusions:ThedecreaseofthestressshieldingrateofSRPinvivowaswellinterrelatedwiththetimeoffixation.TheapplicationofSRPcouldpromotethecallusformationandbonereconstructionthustofavortherecoveryofthemechanicalstrengthoftheunitedbone.

简介：客观：为了调查汽车的效果，控制在试验性的骨折愈合和它的机制上锁钉子(AMLN)的微运动。方法：经历大腿骨的柄的横向的截骨术的双方的16只山羊分别地是有AMLN和Gross-Kempf(GK)钉子的固定intramedullary。后续时间是7，14，28和56天。Roentgenographic，简历机械，组织学，显微镜的扫描电镀物品和生物化学的分析是done.Results：(1)在在修理AMLN的组的fractural结束的反压缩，反屈曲和反扭转的力量比GK修理钉子的组的高；而，在折断的结束的压力躲蔽处的率显著地减少了(P<0.01)。(2)在修理AMLN的组的全部的骨胶原，不可溶解的骨胶原，钙和磷酸盐的内容在GK修理钉子的组比那高(P<0.05)。(3)胼胝的组织学的观察和定量分析表明AMLN能支持桥胼胝和骨膜胼胝的生长。因此愈合的制造和早完成的remolding过程，它比传统的GK好一些钉固定。(P<0.05)。(4)7-14天张贴操作，AMLN-fixedgroup的胼胝繁荣并且camellarly安排了，骨胶原纤丝在骨头trabecula的吸收空隙常常形成了。28-56天柱子操作，骨胶原纤丝是在吸收空隙附近繁荣并且与骨头平行“s纵的轴。活跃多骨的吸收和形成被看见，那么是remolding并且重建。Haversian系统是未经触动的，因为钙盐的免职，多骨的结构的网是很强的。任何一个都没在GK修理钉子的组上述调查结果被观察。结论：AMLN的设计与塑料固定理论一致很好。因为无变态的系统由theintramedullary固定仪器和破裂的近似、远侧的结束组成了的几何学是很坚挺的ands，搁置，到在fractural结束散布的物理压力的骚乱是轻的。在fractural部分之间的断断续续的物理压力的Thegeneration和行为能到达在压力行为和压力保护之间的平衡。特征愈合和remolding同时发生加快愈合的fractural过程。

简介：Inpatientswhohavesustainedtraumaticbraininjurywithassociatedextremityfracture,thereisoftenaclinicalperceptionthattherateofnewboneformationaroundthefracturesiteincreases.Anovergrowthofcallusisobservedandectopicossificationevenoccursinthemuscle,butthemechanismremainsunclear.Whetherthisrapidly-formednewboneisfracturecallusoravariantofheterotopicossification,acommoncomplicationoftraumaticbrain

简介：ObjectiveTo评估未耕作的脂肪质导出stromal的潜在的效果腱healing.MethodsTwenty上的脉管的部分称2.5-3.0kg的五只成年雄的新西兰白兔子被使用。当脂肪质的组织和剩余的施主被划分成控制和治疗组，五只兔子被使用。损害模型被单方的腱切断术通过中间完成三分之一深数字的屈肌腱。立即在缝术以后修理，也新鲜的stromal从脂肪质的织物或安慰剂的酶的消化的脉管的部分intratendinously分别地在治疗和控制组在腱树桩被注射。有演员组的固定在外科以后被继续二个星期。动物在外科以后在八个星期被牺牲，腱经历了组织学，immunohistochemical，和机械评估。量、质的数据的统计分析用变化和Mann-Whitney的单程的分析被估计[/-test，表明的优异纤丝状的线性和连续性，和在处理的减少的由脉管形成组织的respectively.ResultsHistological评估显示了改进组织并且neotendons改变。Immunohistochemistry在骨胶原表明了重要增加我在处理的表示组。最终的负担和精力吸收能力显著地两个都与学习显示出的在场的controls.ConclusionThe相比在对待房间的修理被增加未耕作的脂肪质导出stromal的那intratendinous注射脉管的部分结果在改进了腱修理和它的结构、机械的性质能是为对待腱损害的一种有效形式。