简介:这研究试图评估结果并且描述了cryopreservedlimbal的恢复过程为角膜的外设和limbal疾病的薄片状的keratoplasty(CLLK)。有一个平均数的12个病人的13只眼睛41变老
简介:AIMTo调查在patients.METHODSNon-DSEK在接枝拒绝率,和它的全面程序的有效性上剥去endothelialkeratoplasty(non-DSEK)的non-Descemet的影响在64个病人,和程序的结果的65只眼睛上被执行包括接枝的拒绝事件,失败和脱臼,最好改正的视觉尖酸(BCVA),endothelial房间密度(ECD),和另外的复杂并发症,是65看的分析retrospectively.RESULTSOf,63从bullouskeratopathywi恢复了吝啬的后续时间是26.4mo(范围,6-84mo)。吝啬的BCVA在外科以后在1y在3mo,在6mo的0.46logMAR,和0.37logMAR外科手术前地从1.70logMAR改善了到0.54logMAR。成功地经历了镜子的显微镜的检查的25个病人的手术后的施主ECD是1918<
简介:AIM:Toevaluatetheindications,complications,andvisualandgraftsurvivaloutcomesineyesthathadundergonesimultaneouscataractextractionandpenetratingkeratoplasty(PKP).·METHODS:Wedescribedaretrospectivestudyof101patientswhohadundergonesimultaneouscataractextractionandPKPatKingKhaledEyeSpecialistHospitalbetweenJanuary1,2001,andDecember31,2002.Allpatientswerefolloweduppostoperativelywithmaximumfollow-up68months.·RESULTS:Themeanageofpatientswas61years.Themeanoverallfollow-upwas27months.Themostcommonindicationsforsurgerywerecornealscarring(45.5%),previousfailedgraft(15.8%),cornealulcer(12.9%),Fuchsendothelialdystrophy(8.9%),stromaldystrophy(2.9%),andotherconditions(14.5%).Overall,69grafts(68.3%)remainedclearatfinalfollow-up.Previousglaucomaorpostoperativeglaucomahadnostatisticallysignificanteffectsongraftoutcome(P>0.05).Thegraftrejectionrate(17.8%)wasasignificantriskfactorforfailure(P=0.00).Age,gender,indicationsforsurgery,cornealgraftdiameter,andintraoperativevitreouslosshadnostatisticallysignificanteffectsonthePKPoutcome(P>0.05).Postoperativevisualacuitywassignificantlyassociatedwithpreoperativevisualacuity(P<0.01).·CONCLUSION:Thepresentstudyprovidesevidencethatperformingacombinedprocedureresultsinmorerapidvisualrehabilitationandgoodgraftclarity.
简介:在分数之间的关系在风险分数系统(RSS)获得了的AIMTo分析与渗透keratoplasty(PKP)由希克斯等求婚了在1y的接枝失败手术后地并且在在有PKP接枝失败的风险的RSS的每个因素之中使用univariate和multivariateanalysis.METHODSThe有的回顾的队学习152从152个病人的PKP。十八个盒子由于主要失败(10个盒子)从我们的学习被排除,不完全的医药笔记(5个盒子)和后续不到1y(3个盒子)。我们从134个病人包括了134PKP在外科手术前的风险分数成层。枪兵系数在1y为在获得的分数和失败的风险之间的关系被计算。Univariate和multivariate分析为在1y.RESULTSSpearman系数在接枝失败上在RSS包括的每个单个风险因素的影响被计算在在RSS和接枝失败的分数之间的显示出的统计上重要的关联(P<0.05)。Multivariate逻辑回归分析没显示出统计上重要的关系(P>0.05)在有接枝失败的诊断和透镜地位之间。在因素学习了的另外的风险和接枝失败之间的关系是重要的(P<0.05),尽管以前的接枝的结果和接枝失败是不可靠的。这样,任何一个都没我们的病人有以前的输血它没有impact.CONCLUSIONAftermultivariate分析技术的申请,一些风险因素不在1y在接枝失败上显示出期望的影响。
简介:AIMTo评估剥去与在没有胶囊的support.METHODSDSAEK的严重地损坏的眼睛的透镜(IOL)培植与工匠虹爪IOL培植相结合的工匠缺少晶状体intraocular相结合的自动化endothelialkeratoplasty(DSAEK)的descemet的复杂并发症和结果在29只眼睛上被执行。所有眼睛由于从优先的intraocular手术和眼睛的损伤的复杂并发症具有反常结构。眼睛的复杂并发症观察了包括的接枝脱臼,高intraocular压力(IOP),IOL脱臼,有斑点的浮肿和hyphema。最好改正的视觉尖酸(BCVA),IOP和吝啬的中央endothelial房间密度(ECD)是有的recorded.RESULTSThirteen眼睛眼睛的损伤的历史,10只眼睛有前面的房间IOL,16只眼睛有优先的vitrectomy。虹在22种情况中是反常的。接枝脱臼发生在5(17.2%)29只眼睛。IOL脱臼发生在2只眼睛(6.9%)。高IOP在9只眼睛被发现并且与处理被控制。外科手术前的吝啬的BCVA是20/286。6mo手术后的吝啬的BCVA是20/42。平均中心ECD是在6mo的1965.3房间/公里2,并且施主房间损失的率是与工匠缺少晶状体IOL培植相结合的34.7%.CONCLUSIONDSAEK是为没有胶囊的支持,在aphakic眼睛解决endothelial和透镜混乱的一种其他的选择。然而,它应该与严重的虹缺点为眼睛小心地被执行。
简介:AIMTo在Descemet的家根据厚度评估视觉尖酸和endothelial房间密度剥去自动化endothelialkeratoplasty(DSAEK)在外科以后的年。
简介:AIM:Toassesstheeffectivenessofimmunosuppressantsintheprophylaxisofcornealallograftrejectionafterhigh-riskkeratoplastyandnormal-riskkeratoplasty.METHODS:WesearchedtheCochraneCentralRegisterofControlledTrials(CENTRAL),MEDLINE,EMBASE,CNKI,VIPandreferencelistsofarticles.Dateofmostrecentsearch:18June,2011.Allrandomisedcontrolledtrials(RCTs)assessingtheuseofimmunosupressantsinthepreventionofgraftrejection,irrespectiveofpublicationlanguage.Twoauthorsassessedtrialqualityandextracteddataindependently.Onlydichotomousoutcomes(cleargraftsurvival,ratioofimmunereactionsandsideeffects)wereavailableandwereexpressedasrelativerisk(RR)and95%confidenceintervals(CI).RESULTS:Sevenstudieswereincludedinthisreview.Inthecomparingofmycophenolatemofetil(MMF)withplacebo,theresultsshowedMMFcouldsignificantlyreduceimmunereactionscomparedwithplacebo(RR1.0895%Cl0.95to1.21),butnoeffectoncleargraftsurvival(RR1.1195%Cl0.90to1.35).Incleargraftsurvivalandimmunereactions,MMFandcyclosporineA(CsA)showedsimilareffect(RR1.1195%Cl0.90to1.35,andRR1.48,95%Cl0.56to3.93,respectively).Tacrolimus(FK506)andsteroidshowedsimilareffectsoncleargraftsurvivalandimmunereactions(RR0.32,95%CI0.02to6.21,andRR1.00,95%CI0.88to1.14,respectively).Nodrugrelativesideeffecthasbeenfound.CONCLUSION:MMFmayreduceimmunereactionsinbothnormal-riskandhigh-riskrejectionofpenetratingkeratoplasty.CsAandFK506showedsimilareffectsasMMF.However,duetothelackoflargeclinicaltrials,theevidenceremainweak,thequalityofevidenceswereratedasverylowtomoderate.Large,properlyrandomised,placebo-controlled,doublemaskedtrialsareneededtoevaluatetheeffectofimmunosuppressants.