简介：Intoday'sInternetcomputingworld,illegalactivitiesbycrackersposeaseriousthreattocomputersecurity.Itiswellknownthatcomputerviruses,Trojanhorsesandotherintrusiveprogramsmaycausesevereandoftencatastrophicconsequences.Thispaperproposesanovelsecurecomputerarchitecturebasedonsecurity-code.Everyinstruction/datawordisaddedwithasecurity-codedenotingitssecuritylevel.Externalprogramsanddataareautomaticallyaddedwithsecurity-codebyhardwarewhenenteringacomputersystem.Instructionwithlowersecurity-codecannotrunorprocessinstruction/datawithhighersecuritylevel.Security-codecannotbemodifiedbynormalinstruction.Withminorhardwareoverhead,thenewarchitecturecaneffectivelyprotectthemaincomputersystemfromdestructionortheftbyintrusiveprogramssuchascomputerviruses.FormostPCsystems,itincludesanincreaseofword-lengthby1bitonregisters,thememoryandtheharddisk.

简介：这回为大家介绍一个老牌国外木马．因为不能上网和程序比较狠所以就不拿自己机器做靶子了只给大家简单的介绍介绍功能。解压缩后得到以下两个文件。如图1所示。

简介：Itisproposedthatsomepossiblemacroseismicepicenterscanbedeterminedquicklyfromtherelationshipthatthemicroseismicepicenterslocatedbyinstrumentsbearwithfaults.Basedontheseso-calledmacroseismicepicenters,wecanmakefastseismichazardestimationafterashockbyuseoftheempiricaldistributionmodelofseismicintensity.Incomparisonwiththemethodthatusesthemicroseismicepicentersdirectly,thisapproachcanincreasetheprecisionoffastseismichazardestimation.Statisticalanalysisof133mainearthquakesinChinawasmade.Theresultshowsthatthedeviationdistancebetweenthemicroseismicepicenterandmacroseismicepicenterfallswithintherangeof35kmfor88%earthquakesofthetotalandwithintherangeof35to75kmfortheremainingones.Then,wecantaketheareathathasthemicroseismicepicenterasitscenterandis35kminradiusastheareaforemphaticanalysis,andtaketheareawithin75kmaroundthemicroseismicepicenterastheareaforgeneralanalysis.Therelationbetweenthe66earthquakecasesontheN-SSeismicBeltinChinaandthespatialdistributioncharacteristicsoffaultsandtheresultsoffocalmechanismsolutionwereanalyzedindetail.Weknowfromtheanalysisthattheerrorofinstrumentalepicenterdeterminationisnottheonlyfactorthatgiveseffectstothedeviationofthemacroseismicepicenter.Inadditiontoit,thefaultsize,faultdistribution,faultactivity,faultintersectiontypes,earthquakemagnitude,etc.arealsomainaffectingfactors.Bysortingout,processingandanalyzingtheseaffectingfactors,theprincipleandproceduresforquicklydeterminingthepossiblepositionofthemacroseismicepicenterweresetup.Takingtheseasabasisandestablishinganationwidedatabaseoffaultsthatcontainsrelevantfactors,itispossibletoapplythismethodinpracticalfastestimationofseismichazard.

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简介：AbstractType 1 diabetes (T1D) results from dysfunction of pancreatic islets β cells. Recent studies supported that endoplasmic reticulum (ER) stress takes an important role in pancreatic β cell excessive loss, resulting in T1D. Here, we aimed to review the relationship between ER stress and T1D. Additionally, we also reviewed the potential mechanisms underlying ER stress mediated T1D. Studies have shown that severe ER stress is directly involved in the pancreatic β cells destruction and pathogenesis of T1D. ER stress plays a key part in pancreatic β cells and T1D, which will help in developing new effective therapeutics for T1D.

简介：Thecomplexityofacancer,suchascellheterogeneity,andtheexistenceofhypoxia,stromalcellsandstemcellshaspresent,theuseofconventionaltherapies,suchaschemo/radiotherapyislimited,andonlytherapiesthataresofarpreventedsuccessfuldevelopmentandtreatmentofpatientssufferingfromthelaterstagesofcancers.Atfocusedonutilizingthepatient'simmuneresponsetocombatagainstthediseaseappeartobethemostreliableandpromising.Twodecadesago,cytokineswerediscoveredtobeabletoactivatetheimnunesystemsandmountananti-tumourresponse.Then,dendriticcellswerehailedasthemostsignificantregulatorsofimmunityandareemployedinavarietyofcancermanagementschemes.Thisreviewintroducescurrentdevelopmentinthefield,focusingoncombinationofthecomponentsoftherapidlygrowingfieldsofimmunotherapyandgenetransfer/therapy,providingusefulandsignificantdetailedinformationforreadersofcellularandmolecularimmunology.Cellular&MolecularImmunology.

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