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简介：Withthedevelopmentofmetropolitanregionsandtheappearanceofurbanagglomerations,citieshavebeenmorecloselyrelated.Fortherestrictedemergencyrescueresourceinasinglecity,ithasbecomemoreandmoreimminentforthedemandoftheintercitycollaborativeresistancetomajoraccident,soastoimprovetheprotectioncapacityofurbansecurity.Inordertofindaneffectiveintercityemergencyrescuecollaborativesystem,thispaperintroducestheconceptandanalysismethodofecosystemtheoryintointercityemergencyrescue.Basedontheanalysisoftheformation-processofemergencyrescueindividual,populationandcommunity,athree-levelintercityemergencyrescuecollaborativesystemisconstructedaccordingtothecharacteristicsofdynamicsandstructureofintercityemergencyrescueecosystem,thenthecollaborationmechanismofinformation,resourceandprocessintheintercityemergencyrescueecosystemisalsostudiedinthispaper,soastoofferavailablestrategyandmethodfortheecosystemtheoryappliedtointercityemergencyrescue.Throughthestudiesofintercityemergencyrescueeco-system,itilluminatesthattheproposedemergencysystemcannotonlycopewiththemajoraccidentmoretimelyandeffectively,butalsointegratetheintercityinformationresourcesandemergencyrescueresourceandprocessoptimization.

简介：Objective:Toexploreatreatmentapproachforseverelyinjuredlowerextremities.Methods:Thedataof42patientswithseverelytraumaticlowerextremitiesfrom1989to1999wereretrospectivelyreviewed.AccordingtoMESS(mangledextremityseverityscore)themeanscoreofallthelimbswas6.24±1.45,34caseshadMESSscore<7and8caseshadMESSscore≥7.Treatmentapproachesincludedmicrovascularanastomosistechnique,compoundtissueflaptransplantationtechniqueandcompoundbonetissueflaptransplantation.Conclusions:Successfulemergencytreatmentofseverelyinjuredlowerextremitiescouldbeachievedbyusingmicrosurgerytechniquesandstrictcontrollingoflowerextremitysalvagelindications.

简介：Itisanimportantcontrolprocesstooperatemotionofansubmergencerescuevehicle(SRV).Seeingthatthemotionofthesubmergencerescuevehicleisspecial,itisnecessarytoemploynon-linearpredictivecontrolsystem.Forthisreason,continuousdynamicperformanceofthesystem,thelogicalcomponentsandtheoperativerestraintsareexpressedasthenon-linearequationsofstatewiththeinequalityrestraints,andthemodelprincipleofhybridsystemisintroduced.TheconclusionshowsthatitcomestruetoexactlycontrolpositionandattitudeoftheSRVbymeansofnon-linearmodelpredictivecontrol.Thetestinamodelbasinhasalsoprovedthattheabovemethodsareefficient.

简介：Thispaperaimsatestablishingtheoperationideabasedontheanalysisoftheconnotation,principlesandreferenceindexesforprogrammingstandardforecologicalrescue.Thepaperputsforwardthattheprogrammingstandardshouldtakeintoaccountthenatural,socialandeconomicreferenceindexes,andmodifiesthescaleanddistributionoftheecologicalrescueaccordingtotheorderofecologicalsafety,socialsafetyandeconomicdevelopment.Thepapersuggeststhatthelandplanningdepartmentshouldstrengthenthestudyanddatumaccumulationinordertoestablishthetechnologyregulationsofprogrammingstandardoftheecologicalrescue.

简介：Recently,weinterviewedCewangJigmei,PresidentoftheTibetAcademyofSocialSciences,ontheeffortsTibethasmadetosaveKingGesar.QUESTION:The31stUNESCOSessionheldinParisinOctober2001decidedunanimouslytoincludeactivitiestocelebratethemillenniumanniversaryofKingGesarinthelistofprojectsundertakenwithUNESCOinvolvementin2002-2003.Couldyoupleasetellmeyourviewsonthis?ANSWER:Thisshowstheinternationalrecognitionof,andappreciationfor,theprogress

简介：在蚕，白鸡蛋1(w-1)异种，被白眼睛和白鸡蛋描绘，在Bombyxkynurenine3-monooxygenase(KMO)是缺乏的活动。Toinvestigatew-1异种显型是否被介绍野类型的KMO基因救，我们在细胞质的肌动朊基因倡导者(A3KMO)或本国的KMO基因倡导者(KKMO)的控制下面与野类型的BombyxKMO基因构造了转基因的蚕。我们与KKMO构造与A3KMO和一根线创造了二根转基因的线。在这些线的成年人的眼睛是棕色的，并且转基因的女性生的鸡蛋也是棕色的。Reversetranscription聚合酶链反应(RT-PCR)分析证明A3KMO蚕线在中间勇气的、胖身体表示了抄本，并且肾小体小管。KKMO线仅仅在胖身体表示了抄本并且肾小体小管。在转基因的线的眼睛和卵色的紧张与KMO表示水平成正比。有趣地，有A3KMO构造的转基因的幼虫有轻褐幼虫的表皮，而是KKMO线不。这些结果显示野类型的KMO基因能作为标记基因被使用视觉上屏蔽转基因的蚕。

简介：MCM10蛋白质是涉及DNA的开始的一个必要复制因素。开始发育的酵母的mcm10异种(mcm10-1)在37度C显示出生长拘捕。在现在的工作，我们孤立mcm10-1压制或拉紧，它在37度C成长。有趣地，这mcm10-1压制或在14度C经历房间周期拘捕。新奇基因，YLR003c，被这的高拷贝的互补识别压制或。我们作为Cms1(看10Suppressor的互补)叫了它。而且，转变的实验证明mcm10-1的房间压制或在14度C与高拷贝的原生质标志然而并非低拷贝的原生质标志成长，在Cms1的表示上显示那能救这mcm10的生长拘捕压制或在非容许的温度。这些结果建议那CMS1蛋白质可以机能上地与MCM10蛋白质交往并且在DNA和房间周期控制的规定起一个作用。

简介：进房间的siRNA的有效、稳定的交货，和为siRNA的非特定的离开目标效果的适当控制是到用siRNA技术的功能的研究的主要限制。克服这些缺点，我们开发了能并发地弄空的单个lentiviral向量内长的基因表示当在一样的房间表示标注epitope的siRNA抵抗的目标基因时。表明这个系统的功能的实用程序，我们执行了弄空RNAi的-actinin-1(在人的T房间的-ACTNl)表示。-ACTNlRNAi导致了禁止的趋化性到SDF-l，但是它能被RNAi抵抗的-ACTNl的并发的表示完全救(rr--ACTNl)在一样的房间。rr上的一个GFP标签的存在--ACTNl允许rr的适当subcellular本地化的察觉--ACTNl。这个系统为快速的结构功能分析和基因治疗为RNAi离开目标效果，而且潜在的工具提供不仅内部控制。

简介：Theimplementationofwirelesstechnologiesbasedonthevehicularadhocsensornetwork(VASNET)mayprovidesupportforthesearchandrescue(SAR)teamtooperateeffectivelyinnaturaldisasterevents,suchaslandslide,earthquake,flooding,andtsunami.TheoperationsofSARteamareverychallenginginsucheventsduetothepossibledamagesoftheexistingtelecommunicationinfrastructures.Theexistingdeploymentofthecellularcommunicationsinfrastructuremaybepartiallyorcompletelydestroyedaftertheoccurrenceofthesenaturaldisasters.Thus,thecurrentVASNETinfrastructuremustbeabletosupporttheinfrastructure-lessnetworkbyintegratingothergreenwirelesstechnologiesthatcanbenefittheSARteam,whichcanindirectlysavemorehumanlivesandreducethenumberofcasualties.Therefore,theintegrationofgreenInternetofthings(IoT)andVASNETisproposedtoformaheterogeneousframeworkfordatadisseminationinSARoperations.Inaddition,thispaperalsodiscussestheexistingIoTframeworkindisasterscenarioswithfutureresearchdirectionforIoTusingonanyaspect,especiallyrelatedtothenaturaldisasterscenarios.

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简介：AbstractBackground:High-dose dual therapy (HDDT) with proton pump inhibitors (PPIs) and amoxicillin has attracted widespread attention due to its favorable efficacy in eradicating Helicobacter pylori (H. pylori). This study aimed to compare the efficacy and safety of high-dose PPI–amoxicillin dual therapy and bismuth-containing quadruple therapy for H. pylori rescue treatment.Methods:This was a prospective, randomized, multicenter, non-inferiority trial. Patients recruited from eight centers who had failed previous treatment were randomly (1:1) allocated to two eradication groups: HDDT (esomeprazole 40 mg and amoxicillin 1000 mg three times daily; the HDDT group) and bismuth-containing quadruple therapy (esomeprazole 40 mg, bismuth potassium citrate 220 mg, and furazolidone 100 mg twice daily, combined with tetracycline 500 mg three times daily; the tetracycline, furazolidone, esomeprazole, and bismuth [TFEB] group) for 14 days. The primary endpoint was the H. pylori eradication rate. The secondary endpoints were adverse effects, symptom improvement rates, and patient compliance.Results:A total of 658 patients who met the criteria were enrolled in this study. The HDDT group achieved eradication rates of 75.4% (248/329), 81.0% (248/306), and 81.3% (248/305) asdetermined by the intention-to-treat (ITT), modified intention-to-treat (MITT), and per-protocol (PP) analyses, respectively. The eradication rates were similar to those in the TFEB group: 78.1% (257/329), 84.2% (257/305), and 85.1% (257/302). The lower 95% confidence interval boundary (–9.19% in the ITT analysis, –9.21% in the MITT analysis, and –9.73% in the PP analysis) was greater than the predefined non-inferiority margin of –10%, establishing a non-inferiority of the HDDT group vs. the TFEB group. The incidence of adverse events in the HDDT group was significantly lower than that in the TFEB group (11.1% vs. 26.8%, P < 0.001). Symptom improvement rates and patients’ compliance were similar between the two groups.Conclusions:Fourteen-day HDDT is non-inferior to bismuth-containing quadruple therapy, with fewer adverse effects and good treatment compliance, suggesting HDDT as an alternative for H. pylori rescue treatment in the local region.Trial registration:Clinicaltrials.gov, NCT04678492.