简介:Primaryhemifacialspasm(HFS)isadisorderthatcausesfrequentinvoluntarycontractionsinthemusclesononesideoftheface,duetoabloodvesselcompressingthenerveatitsrootexitzone(REZ)fromthebrainstem.Numerousprospectiveandretrospectivecaseserieshaveconfirmedtheefficacyofmicrovasculardecompression(MVD)ofthefacialnerveinpatientswithHFS.However,whileMVDiseffective,therearestillsignificantpostoperativecomplications.Inthispaper,recenttechnologicaladvancesrelatedtoMVD(suchaslateralspreadresponse,brainstemauditoryevokespotential,threedimensionaltimeofflightmagneticresonanceangiography,intraoperativeneuroendoscopy)arereviewedforthepurposesofimprovingMVDtreatmentefficacyandreducingpostoperativecomplications.
简介:Objective:Toevaluateunusualpossiblecausesandclinicalpresentationsofhemifacialspasm(HFS).Methods:Theauthorsreviewed1642casesofHFS.Assessmentswerebasedonclinicalfeatures,3-dimensionaltime-of-flightmagneticresonanceangiography,andsurgicalfmdings.Causesotherthanneurovascularcompressionattherootexitzoneofthefacialnervewereinvestigatedandunusualclinicalpresentationswerenoted.Results:Nine(0.5%)patientshadasecondarycausativestructurallesion,7patientshadatumor,andtheremaining2hadavascularmalformation.Directcompressionbydolichoectaticvertebrobasilararterywasnotedin
简介:Facialspasmisclinicallyacommonlyen-counteredandobstinatedisease.Thisdiseasewastreatedbymildacupuncturewithasatisfac-torytherapeuticeffect,assummarizedinthefollowing.GENERALDATATherewere87casesintotalinthisseries,52males.and35females.Theoldestandtheyoungestpatientswere60and28yearsoldre-spectively.Thelongestandtheshortestcourses
简介:Objective:TodiscussthemechanismofcerebralvesselspasmcausedbyconcussionandtheeffectofNimodipineonconcussion.Methods:Atotalof224patientswhoweretreatedfromMarch1995toOctober1999weredividedintotwogroupsrandomly,ie.Nimodipinegroup(113cases)andcontrolgroup(11cases).Middlecerebralartery(MCA),basilarartery(BA)andtheaveragepeakforwardvelocityofcerebralbloodflowwereobservedbycolorthree-dimensionaltranscranialDoppler(3D-TCD)within24hoursafteradmissionandattheendof3-6daysoftreatment.Cerbralbloodflowchanges,characteristicsandtreatmenteffectwereanalyzedanddeterminedbyclinicalmainsymptomdisappearancerate.Results:Inconcussion,cerebralbloodflowwasdividedinto3phases:cerebralbloodflowlowinfusiondilationphase,cerebralbloodvesselspasmphaseandcerebralbloodflowrecoveryphase.IntheNimodipinegroup,clinicalmainsymptomdisappearanceratewashigherthanthatinthecontrolgroupinthecerebralspasmandrecoveryphaseswithasignificantdifference(P<0.01).Conclusions:Cerebralvesselspasm,hypoxiaandischemialesionarethemainpathologicalchanges.Whethercerebraldysfunctionisreversibleornotismainlydeterminedbyspasmtimeofcerebralbloodvessel.Nimodipinehasagoodeffectonreleasingspasmanddiminishingthecerebralbloodfolwvelicity.Itnotonlyimprovescurativeeffectonconcussion,butalsoreducesandpreventsconcussionsequelae.Hence,concussionpatientswhohavecerebralspasmconfirmedby3D-TCDshouldbegivenNimodipineroutinelyandearly.
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简介:IntroductionandPatientDescription,Assessmentofpatientswithanginapectorisisachallengefortheclinicalcardiologist.Myocardialischemiaandanginapectoriscanbecausedbyvariousmechanisms,suchascoronaryatherosclerosis,vasospasm,orcoronarymicrovasculardysfunction[1].Moreover,thesemechanismsmayoverlapinagivenpatient,makingitdifficulttodeterminethecauseofangina.Wereportherethecaseofa57-year-oldfemalepatientwithahistoryofanginapectoristhatstarted3monthspreviously.Hersymptomsoccurredpredominantlyatrestbutalsowitheffort.Thepatientwasanactivesmokerwhosmokedabout15cigarettesperday(~20packyears).Moreover,shehadhypertensiontreatedwithenalapril.HerLDLlevelwas75mg/dlwithoutanycholesterol-loweringtherapy.Shewassentfordiagnosticcoronaryangiographyforsuspectedstenosingcoronaryarterydisease.
简介:IntroductionMyocardialischemiaandanginapectoriscanbecausedbyvariousmechanismssuchascoronaryatherosclerosis,vasospasmorcoronarymicrovasculardysfunction[1].Weherereportacaseofa56-year-oldfemalepatientwithahistoryofpreviouspercutaneouscoronaryinterventions(PCI)whoreportedrepetitiveattacksofrestingangina.Coronaryriskfactorsincludedhypertension,hypercholesterolemia(LDL=97mg/dLonatorvastatin),ex-smoker(ceased2013),andapositivefamilyhistory(fatalmyocardialinfarctioninfatheraged52yearsandbrother59years).