简介:目的:探索一种临床实用的前房深度相对定量测量法,初步确定老年人前房深度的正常参考值。方法:裂隙灯光源外转45°,受检眼直视裂隙光,在6点时钟方向测量六个点的前房深度(ABCDEF),以角膜缘处的角膜厚度(CT值)为1计。A:角巩膜缘黑白交界处;B:A点上移1CT;C:B点上移1CT;D:虹膜最高点;E:瞳孔缘;F:晶状体前极。测量了50~75岁的正常老年人,229例229眼,采用双盲法对22例44眼进行了11次重复性检测。结果:女性组ABCDEF点的前房深度均值分别为0.38,0.58,0.89,2.10,2.65和3.26CT;男性组分别为0.71,1.02,1.43,2.37,2.90,3.41CT。女性组每个点的深度均比男性浅(P〈0.05),越近周边部越显著。结论:前房深度六点相对定量测量法可重复性好,实用性强。
简介:目的调查报告安徽省六安市眼外伤病人的流行病学状况及治疗效果.方法对280例(289眼)眼外伤住院病人进行回顾性分析,分析眼外伤病人流行病学状况、治疗效果,有针对性的做好防治工作.结果目前,六安市眼外伤病人仍以穿通伤为主,约占60%,并逐年增加,年龄分布以儿童及青少年为主.职业以农民、儿童、学生为主.治疗效果较以往明显提高,其中暴力伤的治疗效果差,最终视力预后与是否伴有黄斑部损害及视网膜脱离有关,与入院时视力无关.结论B超、CT、MRI等辅助检查应用,显微手术、玻璃体手术,及时的药物治疗是决定最终治疗效果的关键.安全教育、医疗保险制度、防护镜使用是减少眼外伤的发病率并提高眼外伤最终治疗效果的主要因素.
简介:AIM:Tocomparetheeffectoftopicallyadministeredandsubconjunctivallyinjectedbevacizumabonexperimentalcornealneovascularizationinratsfortwoweeksaftertreatment.METHODS:Twenty-eightSprague-Dawleyratsweredividedintofourgroupsof7animals.Eachcornealcenterofrighteyewascauterizedwithsilver/potassiumnitratefor8s.Aftercornealburning,bevacizumab(12.5mg/mL)wastopicallyadministeredthreetimesperday(TBgroup)fortwoweeksorsubconjunctivallyinjectedondays2and4aftercauterization(0.02mL;SBgroup).Asnegativecontrols,ratsreceived0.9%salinetopicallythreetimesperday(TSgroup)orsubconjunctivallyondays2and4(0.02mL;SSgroup).Digitalphotographsofthecorneaweretaken1and2weeksaftertreatmentandanalyzedtodeterminetheareaofcorneacoveredbyneovascularizationasthepercentageofcornealneovascularization.RESULTS:Oneweekaftertreatment,thepercentageofcornealneovascularizationwassignificantlylowerintheTBandSBgroupsthanintheTSandSSgroups(allP<0.05).Twoweeksaftertreatment,thepercentageofcornealneovascularizationwassignificantlylowerintheTBgroupthanintheTSgroup(P<0.05).Inallgroups,thepercentageofneovascularizationwasdecreasingastimepassed(allP<0.05)CONCLUSION:Topicallyadministeredbevacizumabhaslongerstandinganti-angiogeniceffectthansubconjunctivallyinjectedbevacizumabincornealneovascularizationfollowingchemicalinjuryinrats.