简介:Modelinglog-mortalityratesonO-UtypeprocessesandforecastinglifeexpectanciesareexploredusingU.S.data.IntheclassicLee-Cartermodelofmortality,thetimetrendandtheage-specificpatternofmortalityoveragegrouparelinear,thisisnotthefeatureofmortalitmodel.Toavoidthisdisadvantage,O-Utypeprocesseswillbeusedtomodelthelog-mortalityinthispaper.Infact,thismodelisanAR(1)process,butwithanonlineartimedriftterm.BasedonthemortalitydataofAmericafromHumanMortalitydatabase(HMD),mortalityprojectionconsistentlyindicatesapreferenceformortalitywithO-UtypeprocessesoverthosewiththeclassicalLee-Cartermodel.Bymeansofthismodel,thelowboundsofmortalityratesateveryagearegiven.Therefore,lengtheningofmaximumlifeexpectanciesspanisestimatedinthispaper.
简介:摘要:“创新是一个民族的灵魂”,随着人工智能的不断发展和深化,小学信息技术课程标准中添加了程序设计模块,目标是为了让孩子理解编程的基本思想,培养学生发现问题、分析问题、解决问题和学生的创造能力。
简介:OriginDublin,IrelandGenresAlbumRock(专辑摇滚)AlternativePop/Rock(另类流行/摇滚)CollegeRock(学院摇滚)Pop/Rock(流行/摇滚)Post-Punk(后朋克)MembersPaulHewson(laternicknamed"BonoVox"andeventuallyjust"Bono",bornMay10,1960)DaveEvans(laternicknamed"TheEdge",b.August8,1961)AdamClayton(b.March13,1960)LarryMullen,Jr.(b.October31,1961)能够在20多年里不断取得商业上的成功同时又受到乐评人认可的乐队,全世界并没有几个,而U2正是这少数中的一员。U2将自己的音乐理念和商业因素结合,在音乐界取得了非凡的成就。从乐队创建之初一直到现在,U2打破了摇滚乐队和摇滚乐的固有界限,他们用原创音乐配以诚恳的歌词,探讨敏感的社会话题,赢得了同行和乐评人的尊敬,在全世界拥有无数狂热的支持者。下面就是他们的故事。
简介:AheateddebatearoseonthenatureofChina-U.S.relationsamongscholarsinthetwocountries.Arethetwo"strategicpartners"?"Competitors"?"Neitherfriendsnorenemies"?Oreven"Potentialenemies"?Butlargelysince1997,alongwiththeestablishmentoftheframeworkfor"aconstructivestrategicpartnership",thedefinitionseemstohasbeenacceptedbythemainstreamintheChineseacadem-iccircle.Bycontrast,GovernorGeorge.W.Bush,theRepublicanpresidential
简介:WhentheU.S.militarybrassassertedinmid-2014thattheproposeddefensecutbackswereunacceptable,theysignaledtheObamaadministrationthattheywouldnotrolloverandplaydeadwhilemilitaryspendingwascutbybillionsofdollarsinthecoming10years.Theterms"sequestration"and"OCO"wereusedrepeatedlyintheirspeechesand
简介:Militarily,noonehassuspectedthatAmerican-BritishcoalitionforceswouldwintheirwaragainstIraq.Butbefore,duringorafterthewar,thereexistedsomeuncertainties,whichareconcerningthefutureworldstructure,thefutureoftheUnitedStatesitself,theMiddleEast
简介:TheIrannuclearissuehasbecomethe'thirdfactor'inSino-U.S.relations.ProblemsbeganwhentheU.S.imposedsanctionsagainstChinesecompanies,andthisbecameamajorissueaffectingSino-U.S.relationship.ChinaandtheU.S.havedifferentagendasindealingtheIrannuclearissue.However,theyalsosharesomecommonground.DifferentscenariosregardingthelrannuclearissueaffectSino-U.S.relationsindifferentways.
简介:Sincethetopicsofsecurityandcounter-terrorismhaddominatedtherecentU.S.presidentialcampaignanddrawnthepublicattention,2004U.S.presidentialelectionwasalsoakindofreferendumonthenewsecuritystrategyandmilitarystrategypracticedbytheBushadministration.Bush'sreelectionindicatesthattheU.S.militarystrategywillbeconsistentratherthanchangeable,withthefeaturesof"generalconsistencywithpartialadjustments;clearobjectiveswithflexibletactics;unilateralistorientationwithmultilateralapproaches;predeterminedevolutionwithincreasedrestraints."Indetailthetrendsareasfollows:
简介:摘要:随着科技的发展,医学影像设备也正在发生着重大的变化和挑战,应用范围越来越广,性能也在不断提高,功能更趋完善。现代影像设备已经被广泛应用在临床检查、诊断,为医务工作者对患者的诊断和治疗有了非常好的可靠的依据。研究医学图像的人员和医务工作者都希望图像的分析能够显示在屏幕上以便进行分析,这有更加直观、形象的视觉效果。经过十几年的发展,医学诊断设备已经从辅助诊断发展成为辅助治疗的重要手段,并已深入到医学的各个领域。
简介:目的探讨Evi1基因在不同级别胶质瘤组织中的表达,以及调控该基因对胶质瘤细胞株U87和U251细胞增殖、细胞周期和侵袭影响,为靶向癌基因治疗胶质瘤提供客观依据。方法首先通过实时定量PCR(qRT-PCR)分别检测人脑不同级别胶质瘤组织以及U87和U251细胞株中Evil基因的表达水平。用合成的小分子干扰RNA(smallinterferingRNA,siRNA)干扰下调U87和U251细胞Evi1基因表达作为干扰组,同时设空白和阴性对照组。qRT-PCR检测转染前后Evi1基因在U87和U251细胞中的表达和转染效率。CCK-8法检测实验组细胞的增殖能力,流式细胞仪分析FlowCytometer(FCM)其细胞周期。Transwell以及划痕试验检测各组U87和U251的侵袭和迁移能力。以及用qRT-PCR分析下调Evi1基因后U87和U251细胞基质金属蛋白酶2(MMP2)的表达水平。结果Evi1基因在胶质瘤组织中呈现高表达,且随着胶质瘤级别程度增加其表达水平亦上升,其中Ⅲ和Ⅳ级的胶质瘤组织以及U87、U251细胞Evi1基因表达明显高于非瘤脑组织(均P〈0.05)。通过siRNA下调Evi1基因后,胶质瘤细胞株U87和U251的增殖减缓(均P〈0.05),其侵袭和迁移能力明显下降(均P〈0.01),并能阻滞其细胞周期G1期(P〈0.05)。干扰组U87和U251细胞MMP2表达水平明显降低(均P〈0.01)。结论Evi1基因在胶质瘤中呈高表达,干扰U87和U251细胞Evi1基因可抑制胶质瘤的增殖和侵袭。
简介:摘要随着时代的发展,钢结构在建筑工程中得到越来越广泛的应用,本文介绍了U形废钢料槽的制作加工工艺一级制作过程中的重点难点,重点对施工过程中的技术要点进行概述和分析。