简介：BackgroundChronickidneydisease(CKD)patientsareathighriskofatherosclerosis.Structuralandelasticchangesofcarotidarterywallreflecttherangeanddegreeofatherosclerosisinperipheralarteries,whichcanbeacquiredbyultrasoundradiofrequency-datatechniqueautomaticallyandprecisely.MethodsAtotalof66CKDpatientswithnegativeresultsonroutinecarotidarteryultrasoundexaminationwereenrolled,and30healthyphysicalexamineeswereselectedascontrols.Patientsweredividedinto3groupsaccordingtoCKDstage:stage1-2,stage3-4andstage5.Clinicalcharacteristicsandthelaboratoryresultswereacquired.Intima-mediathickness(IMT)andcompliancecoefficient(CC)ofcommoncarotidarteryweremeasuredbyultrasoundradiofrequencydatatechnique(QIMTandQAS).PredictorsofIMTandCCwereanalyzedrespectively.ResultsAmongthe66patients,15wereonstage1-2,15onstage3-4and36onstage5accordingtoeGFR.ThecommoncarotidarteryIMT(CCIMT)ofalltheCKDgroupsexceptpatientsonstage1-2wassignificantlyincreasedwhencomparedwithcontrols.TheCCofcarotidarterysignificantlywasdecreasedineveryCKDgroupcomparedwithcontrols.AgeandCKDstageweresignificantpredictorsofCCIMTandCCinCKDpatients(P<0.05).AgingandadvancedCKDstagewereassociatedwithincreasedCCIMT(OR=4.855and4.969)anddecreasedCC(OR=32.178and14.068).ConclusionsRadiofrequency-datatechniquecandetectthesmallchangesofstructureandelasticityofcarotidarterywallinCKDpatients.CKDpatientshaveincreasedIMTanddecreasedelasticityofcarotidarterycomparedwithhealthysubjects.AgingandadvancedCKDstageareassociatedwithincreasedCCIMTanddecreasedCC.

简介：Radiationexposureisahazardforpatientsandphysiciansduringfluoroscopically-guidedprocedures.Invasivecardiologistsareexposedtohighlevelsofscatterradiationandbothincreasingproceduralcomplexityandhigheroperatorvolumescontributetoexposureaboverecommendedthresholds.Standardshieldingdoesnotoffersufficientprotectiontotheheadandneckregionandthepotentialfornegativebiological,subclinical,andclinicaleffectsexists.Largepopulationstudiessuggestthatcranialexposuretolowdoseradiationincreasestherisksoftumordevelopment.Inaddition,modestdosesoftherapeuticcranialradiationhavebeenlinkedwiththedevelopmentofbraincancer.Althoughacausalassociationbetweenscatterradiationinthecathlabandbraincancerdoesnotcurrentlyexist,giventheknowndetrimentaleffectsofradiationexposuretotheheadandneckregionsupportafocusonpotentialmethodsofprotectionforboththepatientandtheoperator.