The difference of endothelial adherence between the clinical and commensal strains of Staphylococcus epidermidis-中国期刊网

摘要 Staphylococcusepidermidisisoneoftheleadingpathogensofnosocomialinfections.Twenty-eightstrainsofbiofilm-negativeStaphylococcusepidermidis,ofwhichthirteenstrainsconsideredastheclinicalstrainswereisolatedfromcatheters,bloodandurineofpatientsinHuashanHospital(Shang-hai,China)andfifteenstrainsconsideredascommensalstrainswereisolatedfromtheskinofhealthystudentswhohadnocontactwithhospitalsinrecenthalfyear,wereinvestigatedfortheadherencetohumanumbilicalveinendothelialcelllineECV304andhumancervicaladenocareinomacelllineHela,respectively.Ourresultsshowedthattheclinicalstrainsweremuchmoreadhesivetobothcellsthancommensalones.Theendothelialadherencemaybeavirulencefactorassociatedwiththisbacterialpathogenesis.

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The difference of endothelial adherence between the clinical and commensal strains of Staphylococcus epidermidis

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The difference of endothelial adherence between the clinical and commensal strains of Staphylococcus epidermidis

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