Syncope and Early Repolarization:A Benign or Dangerous ECG Finding?

(整期优先)网络出版时间:2016-07-07
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Earlyrepolarizationisawell-described,commonelectrocardiographicvariant.Itwasinitiallyfelttobebenign,butinthelasttwentyyearsasuggestedalinkbetweenspecifictypesofearlyrepolarizationandsuddencardiacdeathhasemerged.ThisassociationwashasbeentermedtheJwavesyndromeandincludesboththehighriskearlyrepolarizationandBrugadaECGpatterns.Theoddsofearlyrepolarizationchangebeingassociatedwithpooroutcomesarestillexceedinglysmall.Nevertheless,theassociationofafairlyubiquitousECGfindingwithfatalornearfatalclinicaloutcomeshasraisedconcern.Howcanweidentifythetrulyhigh-riskpatients?IfapatienthasasignificantclinicaleventwithaconcerningECGrepolarizationpattern,whatshouldbedonenext?TheauthorsofthisreviewpresentcurrentinformationregardingtheEarlyRepolarizationandBrugadaSyndromesandhowtoproceedwithdiagnosis,management,andriskstratificationwhenearlyrepolarizationchangeisobservedonECG.