简介:TheeffectsonhepaticEROD(7-ethoxyresorufinO-deethylase)inMugilso-iuyexposedtobenzo(a)pyrene(BaP),pyreneandtheirmixturesofequalconcentrationwereinvestigated,atconcentrationsof0.1,1.0,5.0,10.0,50.0μg/dm3,inexperimentalcondition.Time-effectsanddoseresponseofthebiochemicalindexswereobserved.TheresultsshowedthatthehepaticERODactivitieswereinducedbytheexposureofBaP,pyreneandtheirmixturesathighconcentration.Dose-responseconnectionswerethatthehepaticERODactivitieswereelevatedwithincreasingconcentrationofthepollutants.ThecombinedeffectofBaPandpyreneat1:1concentrationratioonhepaticERODactivitywasantagonism.