简介:对化合物[Na_2(H_2O)_(10)][Cu_4(H_2O)_(12)(H_2W_(12)O_(42))]·15H_2O(简称Na_2Cu_4W_(12))进行了体外抗肿瘤活性研究.应用四甲基偶氮唑盐(3-[4,5-dimethylthiazo-2-y]-2,5-diphenyltetrazoliumbromide,MTT)比色法分析Na_2Cu_4W_(12)对人肝癌细胞(HepG2)、人神经母细胞瘤细胞(SHY5Y)增殖抑制活性.采用光学显微镜观察肿瘤细胞的凋亡形态变化,用流式细胞术分析细胞周期和细胞凋亡,计算各期细胞比例及细胞凋亡率.结果表明,Na_2Cu_4W_(12)对HepG2和SHY5Y2种肿瘤细胞增殖半数抑制浓度IC_(50)值分别为5.3和10.2μmol·L~(-1),且呈剂量依赖性.光学显微镜下处理组细胞出现皱缩、变圆、缩小等形态变化,不同浓度Na_2Cu_4W_(12)处理12h早期凋亡细胞所占的百分比显著增加且呈剂量依赖性.综上所述,Na_2Cu_4W_(12)能够抑制胞瘤细胞增殖,诱导细胞凋亡.
简介:Inthispaper,wefirstshowtheglobalexistence,uniquenessandregularityofweaksolutionsforthehyperbolicmagnetohydrodynamics(MHD)equationsinR~3.ThenweestablishthatthesolutionswithinitialdatabelongingtoH~m(R~3)∩L~1(R~3)havethefollowingtimedecayrate:║▽~mu(x,t)║~2+║▽~mb(x,t)║~2+║▽~(m+1)u(x,t)║~2+║▽~(m+1)b(x,t)║~2≤c(1+t)~(-3/2-m)forlarget,wherem=0,1.
简介:Firstly,theRiemannboundaryvalueproblemforakindofdegenerateellipticsystemofthefirstorderequationsinR~4isproposed.Then,withthehelpoftheone-to-onecorrespondencebetweenthetheoryofCliffordvaluedgeneralizedregularfunctionsandthatofthedegenerateellipticsystem’ssolution,theboundaryvalueproblemasstatedaboveistransformedintoaboundaryvalueproblemrelatedtothegeneralizedregularfunctionsinCliffordanalysis.Moreover,thesolutionoftheRiemannboundaryvalueproblemforthedegenerateellipticsystemisexplicitlydescribedbyusingakindofsingularintegraloperator.Finally,theconditionsfortheexistenceofsolutionsoftheobliquederivativeproblemforanotherkindofdegenerateellipticsystemofthefirstorderequationsinR~4arederived.
简介:SpokecavitieshavebeendevelopedandhaveapparentadvantagesforhighcurrentprotonacceleratorbasedonFig.1(coloronline)Theelectromagneticfielddistribution.superconductivityatlowandmediumenergyregion.Astheresearchandthetechnicalreserve,InstituteofModernPhysics(IMP)hasstartedtheR&Dprogramofadoublespokecavity(operatingfrequency325MHz,0=0.52),withintheframeworkofChinaAcceleratorDrivenSystem(C-ADS)project.TheRFdesignandmechanicalstructuredesignhavebeenfinished,andtwoprototypecavitiesweremanufacturedinHarbin.
简介:Westudytheconsistencyconditionsofthegeneralizedf(R)gravitybyextendingf(R)gravitywithnon-minimalcouplingtothegeneralizedf(R)witharbitrarygeometry-mattercoupling.Specifically,wediscussthetwoparticularmodelsofgeneralizedf(R)bymeansofconsistencyconditions.Itisfoundthatthesecondmodelisnotphysicallyviablesoastoberuledout.Moreover,wefurtherconstrainthefirstmodelusingtheDolgovKawasakistabilitycriterion,andgivethevaluerangesoftheparametersinthefirstmodel.Itisworthstressingthatourresultsincludetheonesinf(R)gravitywithnon-minimalcouplingasthespecialcaseofQ(L_m)=L_m.
简介:以“闪光二号”加速器硬X射线为辐照源,对腔体内系统电磁脉冲(systemgeneratedelectromagneticpulse,SGEMP)磁场环境的验证方法进行了研究。根据测量的“闪光二号”二极管的电压、电流,模拟了发射电子束能谱参数;结合辐射靶物理设计,建立了二极管阳极靶蒙特卡罗粒子输运计算模型,模拟了轫致辐射X射线场参数;采用时域有限差分(finitedifferencetimedomainmethod,FDTD)和粒子模拟(particleincell,PIC)方法,模拟了该射线环境中的腔体SGEMP磁场环境;将轫致辐射X射线参数及腔体SGEMP磁场环境的模拟结果与实验结果进行了比较。结果表明:从X射线源参数模拟开始的腔体内SGEMP数值模拟计算模型的实验验证方法是合理可行的。
简介:本文中,我们研究一类由极大Bochner—Riesz算子和Lipschtz函数A生成的多线性算子,获得了它的(Lp,上q)型,而且我们还将证明此算子从Lebesgue空间到Lipschtz空间、从Herz空间到Campanato空间和从Lp空间到Tribel—Lizorkin空间的有界性.
简介:Recently,Cristofaro-GardinerandHutchingsprovedthatthereexistatleasttwoclosedcharacteristicsoneverycompactstar-shapedhypersufaceinR~4.ThenGinzburg,Hein,Hryniewicz,andMacarinigavethisresultasecondproof.Inthispaper,wegiveitathirdproofbyusingindexiterationtheory,resonanceidentitiesofclosedcharacteristicsandaremarkabletheoremofGinzburgetal.
简介:Thehybridstructuresofpolystyrene-b-poly(ethyleneoxide)(PS-b-PEO)blockcopolymerandinorganicnanoparticleswithgoodstabilityandbiocompatibilityhavepotentialapplicationsindrugdeliveryandbioimaging.Sphericalco-assembliesofPS120-b-PEO318andoleylamine-cappedCdSquantumdots(QDs)areproducedsuccessfullyinthisworkbyaddingwatertoamixedcommonsolvent,suchasN,N-dimethylmethanamide(DMF)/chloroform,DMF/tetrahydrofuran(THF),orDMF/toluene.TheenergydispersiveX-ray(EDX)spectrumindicatesthatQDsarelocatedattheinterfacebetweenthecoreandshellofthesphericalco-assemblies.Theco-assemblyprocessduringwateradditionistracedbytransmissionelectronmicroscopy(TEM)andturbiditymeasurement.Sphericalco-assembliesareformedthroughbuddingfrombilayersoftheblockcopolymerandQDs.Themorphologyoftheco-assembliesisrelatedtothemiscibilityoftheQD-dispersingsolventswithwaterandthemorphologychangesfromasphericaltoavesicle-likestructurewithDMF/toluene.IncreasingTHFcontentinthemixedsolventcausesmorphologicaltransitionsfromsphericalco-assembliestomulti-branchedcylindersandmicelleswhereQDsarelocatedinthecentralcore.Increasingchloroformcontentyieldsvesicle-likestructureswithprotrudingrodsonthesurface.Themechanismofthemorphologicaltransitionsisalsodiscussedindetail.
简介:TypeIX-rayburstsarethemostfrequentthermonuclearexplosionsinnature,resultingfromthermonuclearrunawayonthesurfaceofanaccretingneutronstar[1].Thebreakoutreaction14O(α,p)17FfromthehotCNOcyclemayhaveaprominentimpactontheburstlightcurveandburstashes[2].However,insufficientexperimentalinformationisavailabletocalculateareliable,preciserateforthisreaction[3].Weproposedtoaddresstheexperimentalinvestigationofthe14O(α,p)17FusingTimeProjectionChamber(TPC)[4].
简介:Globallook-uptablestrategyproposedrecentlyhasbeenproventobeanefficientmethodtoacceleratetheinterpolation,whichisthemosttime-consumingpartintheiterativesub-pixeldigitalimagecorrelation(DIC)algorithms.Inthispaper,agloballook-uptablestrategywithcubicB-splineinterpolationisdevelopedfortheDICmethodbasedontheinversecompositionalGauss–Newton(IC-GN)algorithm.Theperformanceofthisstrategy,includingaccuracy,precision,andcomputationefficiency,isevaluatedthroughatheoreticalandexperimentalstudy,usingtheonewithwidelyemployedbicubicinterpolationasabenchmark.Thegloballook-uptablestrategywithcubicB-splineinterpolationimprovessignificantlytheaccuracyoftheIC-GNalgorithm-basedDICmethodcomparedwiththeoneusingthebicubicinterpolation,atatrivialpriceofcomputationefficiency.
简介:The12C+13Csystemhasbeenstudiedextensively,becauseofthesimilarityoftheentrancechanneltotheastrophysicallyimportant12C+12Creaction[1??3].Untilnow,threedifferentmethodshavebeenexploitedtoperformthefusioncrosssectionmeasurementsfor12C+13CundertheCoulombbarrier:(1)measuringtheyieldofcharacteristicrays,(2)thetotal-rayyieldsusingNaIsummingdetectorsand(3)theactivityofthereactionresidue24Na(T1=2=15.0h).Recently,thefusioncrosssectionof12C+13Chasbeenmeasureddownto0.9nbthroughtheactivitymeasurementbyourgroup[4].Althoughthestatisticalmodelcalculationsinallthesethreemethodshavebeenroutinelyusedtoconverttheobservedpartialcrosssectionsintothetotalfusioncrosssections[5],thesystematicuncertaintyinducedbythestatisticalcorrectionshasnotbeenstudiedverywell.