简介:Steadystateandtime-resolvedautofluorescencespectroscopiesareemployedtostudytheautofluorescencecharacteristicsofhumancolonictissuesinvitro.Theexcitationwavelengthvariesfrom260to540nm,andthecorrespondingfluorescenceemissionspectraareacquiredfrom280to800nm.Significantdifferenceinfluorescenceintensityofexcitation-emissionmatrices(EEMs)isobservedbetweennormalandtumorcolonictissues.Comparedwithnormalcolonictissue,lownicotinamideadeninedinucleotide(phosphate)(NAD(P)H)andflavinadeninedinucleotide(FAD),andhighaminoacidsandprotoporphyrinIX(PpIX)fluorescencescharacterizehigh-grademalignanttissue.Moreover,theautofluorescencelifetimesofnormalandcarcinomatouscolonictissuesat635nmunder397-nmexcitationareabout4.32±0.12and18.45±0.05ns,respectively.ThehighaccumulationofendogenousPpIXincoloniccancersisdemonstratedinbothsteadystateandtime-resolvedautofluorescencespectroscopies.更多还原
简介:Anewtime-resolvedshifteddualtransmissiongratingspectrometer(SDTGS)isdesignedandfabricatedinthiswork.ThisSDTGSusesanewshifteddualtransmissiongrating(SDTG)asitsdispersivecomponent,whichhastwosubtransmissiongratingswithdifferentlinedensities,of2000lines/mmand5000lines/mm.TheaxesofthetwosubtransmissiongratingsinSDTGarehorizontallyandverticallyshiftedacertaindistancetomeasureabroadrangeof0.1–5keVtime-resolvedX-rayspectra.TheSDTGhasbeencalibratedwithasoftX-raybeamofthesynchrotronradiationfacilityanditsdiffractionefficiencyisalsomeasured.ThedesignedSDTGScantakefulluseofthespaceonarecordpanelandimprovetheprecisionformeasuringspatialandtemporalspectrumsimultaneously.ItwillbeapromisingapplicationforaccuratediagnosisofthesoftX-rayspectrumininertialconfinementfusion.
简介:Oneofthetechnicalbottlenecksoftraditionallaser-inducedbreakdownspectroscopy(LIBS)isthedifficultyinquantitativedetectioncausedbythematrixeffect.Totroubleshootthisproblem,thispaperinvestigatedacombinationoftime-resolvedLIBSandconvolutionalneuralnetworks(CNNs)toimproveKdeterminationinsoil.Thetime-resolvedLIBScontainedtheinformationofbothwavelengthandtimedimension.Thespectraofwavelengthdimensionshowedthecharacteristicemissionlinesofelements,andthoseoftimedimensionpresentedtheplasmadecaytrend.Theone-dimensionaldataofLIBSintensityfromtheemissionlineat766.49nmwereextractedandcorrelatedwiththeKconcentration,showingapoorcorrelationofR^2c=0.0967,whichiscausedbythematrixeffectofheterogeneoussoil.Forthewavelengthdimension,thetwo-dimensionaldataoftraditionalintegratedLIBSwereextractedandanalyzedbyanartificialneuralnetwork(ANN),showingR^2v=0.6318andtherootmeansquareerrorofvalidation(RMSEV)=0.6234.Forthetimedimension,thetwo-dimensionaldataoftime-decayLIBSwereextractedandanalyzedbyANN,showingR^2v=0.7366andRMSEV=0.7855.Thesehigherdeterminationcoefficientsrevealthatboththenon-KemissionlinesofwavelengthdimensionandthespectraldecayoftimedimensioncouldassistinquantitativedetectionofK.However,duetolimitedcalibrationsamples,thetwo-dimensionalmodelspresentedover-fitting.Thethree-dimensionaldataoftime-resolvedLIBSwereanalyzedbyCNNs,whichextractedandintegratedtheinformationofboththewavelengthandtimedimension,showingtheR^2v=0.9968andRMSEV=0.0785.CNNanalysisoftime-resolvedLIBSiscapableofimprovingthedeterminationofKinsoil.
简介:Adischarge-produced-plasma(DPP)sourceemittingintheextremeultraviolet(EUV)spectralregionisrunningattheENEAFrascatiResearchCentre.Theplasmaisgeneratedinlow-pressurexenongasandefficientlyemits100-nsdurationradiationpulsesinthe10–20-nmwavelengthrange,withanenergyof20mJ/shot/srata10-Hzrepetitionrate.Thecomplexdischargeevolutionisconstantlyexaminedandcontrolledwithelectricalmeasurements,whileansgatedCCDcameraallowedobservationofthedischargedevelopmentinthevisible,detectionoftime-resolvedplasmacolumnpinching,andoptimizationofthepre-ionizationtiming.AccuratelycalibratedZr-filteredPINdiodesareusedtomonitorthetemporalbehaviourandenergyemissionoftheEUVpulses,whilethecalibrationofadosimetricfilmallowsquantitativeimagingoftheemittedradiation.Thiscomprehensiveplasmadiagnosticshasdemonstrateditseffectivenessinsuitablyadjustingthesourceconfigurationforseveralapplications,suchasexposuresofphotonicmaterialsandinnovativephotoresists.
简介:Broadband(1.6–18THz)terahertztime-domainspectroscopy(THz-TDS)andtime-resolvedterahertzspectroscopy(TRTS)wereperformedona54μmthickchalcogenideglass(As30Se30Te40)samplewithatwo-colorlaser-inducedairplasmaTHzsystemintransmissionandreflectionmodes,respectively.Twoabsorptionbandsat2–3and5–8THzwereobserved.TRTSrevealsanultrafastrelaxationprocessofthephotoinducedcarrierresponse,welldescribedbyarateequationmodelwithafiniteconcentrationofmid-bandgaptrapstatesforself-trappedexcitons.ThephotoinducedconductivitycanbewelldescribedbytheDrude–Smithconductivitymodelwithacarrierscatteringtimeof12–17fs,andweobservesignificantcarrierlocalizationeffects.Afastrefractiveindexchangewasobserved100fsbeforetheconductivityreacheditsmaximum,with2ordersofmagnitudelargeramplitudethanexpectedfortheopticallyinducedTHzKerreffect,indicatingthatfreecarriersareresponsibleforthetransientindexchange.
简介:Wedemonstratethatthemethodologyoffrequency-resolvedopticalgating(FROG)isapplicabletotime-resolvedreflectionspectroscopyofaplasmamirrorinthevacuum-ultraviolet(VUV)region.Ourrecentstudy[R.Itakuraetal.Opt.Express23,10914(2015)]hasshownthataVUVwaveformcanberetrievedfromaVUVreflectionspectrogramofaplasmamirrorformedonafusedsilica(FS)surfacebyirradiationwithanintensefemtosecondlaserpulse.Simultaneously,theincreaseinthereflectivitywithrespecttotheFresnelreflectionoftheunexcitedFSsurfacecanbeobtainedasatime-dependentreflectivityoftheplasmamirror.Inthisstudy,weupdatetheFROGanalysisprocedureusingtheleast-squaregeneralizedprojectionsalgorithm.Thisprocedurecanreachconvergencemuchfasterthanthepreviousoneandhasnoaliasingproblem.ItisdemonstratedthatasignificantlychirpedVUVpulseaslongas1pscanbepreciselycharacterized.
简介:第一原则的计算被执行探索一系列graphene-nanoribbon-basednanojunctions的解决纺纱的电子、热电的运输性质。由扭动,处于到反平行的、很大的通道磁致电阻的从平行的graphene领先的磁性的时刻能为所有结构在不同的门电压下面被获得。为短nanojunctions的解决纺纱的交替水流的传导力增加对频率但是为长nanojunctions减少。与增加连接长度,连接的行为从象电容一样改变到象引入一样。因为费密水平附近的旋转起来thermopower和旋转下面thermopower的相反的符号,纯旋转电流能被获得,优点的大数字能被为所有nanojunctions调整门电压和化学潜力完成。
简介: