简介: [摘要 ] 目的 探讨美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎的疗效及其对炎性因子的影响。 方法 选取 2018年 1月~ 2020年 1月我院收治的溃疡性结肠炎患者 80例,随机分为两组,每组各 40例,两组患者均予常规对症治疗,同时两组均予美沙拉嗪缓释颗粒,观察组同时加用双歧三联活菌胶囊,治疗后比较两组患者治疗后的临床疗效,以及两组患者治疗前后 TNF-α、 IL-10水平的变化情况及两组患者治疗前后的临床症状积分变化情况。结果 观察组治疗后的总有效率为 95.00%,显著高于对照组的总有效率 70.00%,两组疗效比较差异具有显著性( P<0.05)。治疗后,两组患者的炎性因子 TNF-α、 IL-10水平较治疗前显著降低( P<0.05)。且观察组患者治疗后的 TNF-α、 IL-10水平显著低于对照组( P<0.05)。观察组患者治疗后的临床症状积分为( 2.56±0.85)分,与治疗前及对照组比较,差异有统计学意义( P<0.05)。 结论 美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎疗效确切,且可以抑制炎症反应,值得临床推广和应用。 [关键词 ] 溃疡性结肠炎 ;美沙拉嗪 ;双歧三联活菌 ;炎性因子 [Abstract] Objective To investigate the efficacy of mesalazine combined with Bifid Triple Viable Bacteria in the treatment of ulcerative colitis and its influence on inflammatory factors. method Methods: 80 patients with ulcerative colitis in our hospital from January 2018 to January 2020 were selected and randomly divided into two groups, 40 cases in each group. Both groups were given conventional symptomatic treatment, while the two groups were given mesalazine sustained-release granules. The observation group was also given Bifid Triple Viable capsules. After treatment, the clinical efficacy of the two groups of patients after treatment, as well as TNF - α, IL-10 water before and after treatment, were compared between the two groups The changes of the two groups of patients before and after treatment of clinical symptoms integral changes. Results the total effective rate of the observation group was 95.00%, which was significantly higher than that of the control group (70.00%). There was a significant difference between the two groups (P < 0.05). After treatment, the levels of inflammatory factors TNF - α and IL-10 in the two groups were significantly lower than those before treatment (P < 0.05). The levels of TNF - α and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05). The clinical symptom score of the observation group after treatment was (2.56 ± 0.85), and the difference was statistically significant (P < 0.05). Conclusion mesalazine combined with Bifid Triple Viable Bacteria is effective in the treatment of ulcerative colitis, and can inhibit inflammatory reaction, which is worthy of clinical promotion and application.
简介:摘要:目的:通过对糖尿病患者用血糖水平、尿微量白蛋白的联合检验,来探讨和分析该种检验方法对于糖尿病患者的早期肾损伤的意义,判断诊断的价值,为以后的类似诊断提供有效的参考和借鉴。方法:选取内分泌科收治的糖尿病患者 45例为观察组,并选择同期进行体检的 45例健康者为对照组。两组患者均进行 血糖及尿微量蛋白水平检测。对比两组患者检测结果。结果:观察组的血糖、尿微量白蛋白两项检验学指标均显著高于对照组(P< 0.05),二者有显著性差异。结论:采用糖尿病早期肾损伤患者采用 血糖、尿微量白蛋白联合检验,诊断效果良好,为临床治疗提供有效依据。
简介:【摘要】目的:探究肝胃郁热型2型糖尿病患者通过格列美脲+二甲双胍+穴位贴敷+大柴胡汤进行辅助治疗的应用价值。方法:摘取我院于2022年1月-2023年1月期间接诊的肝胃郁热型2型糖尿病患者共88例纳入研究,以双色球法将其分成常规组和综合组,每组患者各为44例,常规组主要围绕格列美脲+二甲双胍进行常规治疗,综合组则围绕格列美脲+二甲双胍+穴位贴敷+大柴胡汤展开联合治疗,针对两组病患的治疗效果展开分析。结果:综合组整体有效率明显高于常规组,差异有统计学意义(P<0.05)。结论:临床可以围绕格列美脲+二甲双胍+穴位贴敷+大柴胡汤方案来对肝胃郁热型2 型糖尿病展开综合治疗,有助于血脂和血糖水平的改善,效果显著,值得推广。
简介:摘要:目的:在本次的研究中主要的目的是为了探究在对血液病患者梅毒螺旋体抗体检测当中使用人免疫球蛋白的临床应用价值,并对应用前后的数据进行对比比较。方法:在此次的研究当中,选取的是来我院进行治疗并且被诊断为血液病患者同时具有梅毒螺旋体抗体的样本数52例,选取其中患者注入人免疫球蛋白一共42例,剩下的9例血液病患者则是不使用人免疫球蛋白。通过对这两组人员在使用和没有使用人免疫球蛋白后体内梅毒螺旋体抗体检测的结果进行相互的比较。结果:根据两组人员体内梅毒螺旋体抗体检测数据结果分析能够了解到,在52例样本当中,经过梅毒螺旋体血凝实验检测出具有阳性的一共有10例,被注入人免疫球蛋白的42例患者,经过三种试剂的检测程阳性的概率分别为:强生试剂检测下的阳性率为78.6%、万泰试剂检测下的阳性率为88.1%、索林试剂检测下的阳性率为66.7%,并且在经过梅毒螺旋体血凝实验检测都为阳性。而剩下的9例患者在没有使用人免疫球蛋白的检测结果逐渐的转变为阴性,两组数据之间对比具有较大差异性,差异具有统计学意义,P