简介：AbstractIn vitro maturation (IVM) has been used in clinical settings for 30 years. The merits of IVM include that it needs a relatively small amount of hormones and short treatment period. However, because the effectiveness of IVM is lower than that of controlled ovarian hyperstimulation, there are few centers routinely use IVM, and it is only applicable to a few special populations. In this article, several oocyte sources related to IVM have been discussed and the effects of gonadotropin priming and triggering on IVM are described. Furthermore, we have reviewed the optimization of IVM culture conditions in recent years along with the effects of IVM on genes of oocytes and cumulus cells and the obstetric and neonatal outcomes. We aim to provide indications for future improvement of IVM technology so that the success rates of IVM technology in special populations can be improved. We hope that this mild and natural protocol can be applied to more populations, including individuals with normal ovulation.

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简介：摘要：随着现代社会的发展，教育行业对教师的要求越来越高，教师不仅要具有足够强的专业素养，还要能够对新型教学方式能熟练应用。在OMO模式下的历史教师要对其进行熟练应用，并且能够让学生在该模式下找到最适合自己的学习方法。通过对学生进行OMO模式教学，可以发挥学生的主体地位，并且能够改善师生的关系，让学生能够对教材内容进行熟练掌握与应用。而且还能够增加师生之间的互动，让教师能够有针对性的对学生进行指导。

简介：摘要关于睡眠障碍已有大量相关文献报道，但在儿科尤其是对0～5岁儿童睡眠障碍并没有得到应有重视。为提高儿科医生对0～5岁儿童睡眠障碍的认识，查阅近10年国内外相关文献，并对其临床表现和治疗方法进行综述。0～5岁婴幼儿睡眠障碍临床表现不典型且发病率高，儿科医生对此方面认识较差。睡眠障碍对0～5岁患儿认知行为发育有深远影响。

简介：摘要关于睡眠障碍已有大量相关文献报道，但在儿科尤其是对0～5岁儿童睡眠障碍并没有得到应有重视。为提高儿科医生对0～5岁儿童睡眠障碍的认识，查阅近10年国内外相关文献，并对其临床表现和治疗方法进行综述。0～5岁婴幼儿睡眠障碍临床表现不典型且发病率高，儿科医生对此方面认识较差。睡眠障碍对0～5岁患儿认知行为发育有深远影响。

简介：摘要：0-3岁是幼儿发育的关键阶段，也是开展健康教育的最佳时机。为了幼儿健康发育，关注幼儿心理健康教育，注重情感、性格引导培养，给予幼儿充足的关爱，用“爱”包围幼儿，用“心”引导幼儿，培养幼儿乐观开朗的心态，让幼儿健康快乐长大。在此基础上，本文从幼儿健康的角度出发，探讨健康教育开展策略，为幼儿教育提供参考。

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简介：摘 要：本文研制了一种变电站内带电断接引流线消弧滑车，对连接在导线上的滑车构件进行了改良，能够很好的适用与35-110kV电压等级的断、接引流线工作，有效解决了滑车与导线通流能力的问题。滑车操作上方便灵活，有效降低了工作人员劳动强度，显著提高了工作效率。

简介：摘要：随着素质教育的深入，教师要对以往比较单一的教学方式加以创新，结合小学生对数学学习的实际情况，为小学生搭建出适合的教学模式，让小学生能够深入理解并感悟数学知识，进而增强小学生的探究意识、实践能力和思维能力。本文以“0的乘法”作为教学案例展开探究，分析了数学教学中创新教学思路的策略，以便增强数学教学的效率。

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简介：AbstractDecidualization is a special type of differentiation of endometrial stromal cells into secretory decidualized cells, which is closely related to the occurrence of menstruation and establishment of pregnancy. Decidualization abnormalities can cause female infertility and abortion, and the decidualization model in vitro is an important tool for studying relevant mechanisms. This article summarizes several in vitro decidualization models in recent research from three aspects, including the selection of model cells and culture systems, evaluation of decidualization markers, and induction schemes. These models can be appropriately selected and applied in specific endometrium-related disease models, such as endometriosis, recurrent pregnancy loss, and preeclampsia.

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简介：摘要：自2019年起，早教机构的数量呈井喷式增长，越来越多的父母选择上亲子课程。如何开展优质的亲子课程吸引家长和孩子，成为了教师们必须面对的问题。

简介：摘要：蒙台梭利《童年的秘密》一书是一本了解儿童发育和成长秘密的最生动的著作。蒙台梭利指出:儿童并不是一个只可以从外表观察的陌生人。更确切地说，童年构成了人生中最重要的一部分，因为一个人是在他的早期就形成的。孩子一出生就有了视觉、听觉、触觉、感知觉(本体觉)、前庭觉，利用这些感观，让孩子感知、认识这个世界。

简介：AbstractAlzheimer disease (AD) is the most common type of dementia characterized by the progressive cognitive and social decline. Clinical drug targets have heavily focused on the amyloid hypothesis, with amyloid beta (Aβ), and tau proteins as key pathophysiologic markers of AD. However, no effective treatment has been developed so far, which prompts researchers to focus on other aspects of AD beyond Aβ, and tau proteins. Additionally, there is a mounting epidemiologic evidence that various environmental factors influence the development of dementia and that dementia etiology is likely heterogenous. In the past decades, new risk factors or potential etiologies have been widely studied. Here, we review several novel epidemiologic and clinical research developments that focus on sleep, hypoxia, diet, gut microbiota, and hearing impairment and their links to AD published in recent years. At the frontiers of AD research, these findings and updates could be worthy of further attention.

简介：[摘要]目的：探究8-0可吸收缝线和10-0不可吸收缝线在翼状胬肉术后临床对比效果。方法：将36例进行翼状胬肉术的患者随机均分为两组。观察组10-0不可吸收缝线，对照组8-0可吸收缝线，对比其结膜组织局部增生情况。结果：观察组显著更优，P＜0.05。结论：

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