学科分类
/ 1
10 个结果
  • 简介:AIM:Toassesstheeffectivenessofimmunosuppressantsintheprophylaxisofcornealallograftrejectionafterhigh-riskkeratoplastyandnormal-riskkeratoplasty.METHODS:WesearchedtheCochraneCentralRegisterofControlledTrials(CENTRAL),MEDLINE,EMBASE,CNKI,VIPandreferencelistsofarticles.Dateofmostrecentsearch:18June,2011.Allrandomisedcontrolledtrials(RCTs)assessingtheuseofimmunosupressantsinthepreventionofgraftrejection,irrespectiveofpublicationlanguage.Twoauthorsassessedtrialqualityandextracteddataindependently.Onlydichotomousoutcomes(cleargraftsurvival,ratioofimmunereactionsandsideeffects)wereavailableandwereexpressedasrelativerisk(RR)and95%confidenceintervals(CI).RESULTS:Sevenstudieswereincludedinthisreview.Inthecomparingofmycophenolatemofetil(MMF)withplacebo,theresultsshowedMMFcouldsignificantlyreduceimmunereactionscomparedwithplacebo(RR1.0895%Cl0.95to1.21),butnoeffectoncleargraftsurvival(RR1.1195%Cl0.90to1.35).Incleargraftsurvivalandimmunereactions,MMFandcyclosporineA(CsA)showedsimilareffect(RR1.1195%Cl0.90to1.35,andRR1.48,95%Cl0.56to3.93,respectively).Tacrolimus(FK506)andsteroidshowedsimilareffectsoncleargraftsurvivalandimmunereactions(RR0.32,95%CI0.02to6.21,andRR1.00,95%CI0.88to1.14,respectively).Nodrugrelativesideeffecthasbeenfound.CONCLUSION:MMFmayreduceimmunereactionsinbothnormal-riskandhigh-riskrejectionofpenetratingkeratoplasty.CsAandFK506showedsimilareffectsasMMF.However,duetothelackoflargeclinicaltrials,theevidenceremainweak,thequalityofevidenceswereratedasverylowtomoderate.Large,properlyrandomised,placebo-controlled,doublemaskedtrialsareneededtoevaluatetheeffectofimmunosuppressants.

  • 标签: IMMUNOSUPPRESSANTS PENETRATING KERATOPLASTY META-ANALYSIS
  • 简介:目的对开展国际防盲合作项目中实施项目管理方法进行探讨。方法采用回顾方法对国际防盲合作项目中项目管理方法进行分析。结果国际防盲合作项目中由于采用规范的项目管理,项目实施中无违规现象发生,从而保证防盲合作项目按时、超额完成项目目标,获得极佳项目社会影响并获得项目外方的首肯,项目将可持续发展。结论正确认识和规范国际防盲合作项目进行项目管理,有助于项目开展,合理地分配资源、推广应用项目成果,促成防盲合作项目的可持续发展,所以建立国际防盲合作项目管理体系是可行及必要的。

  • 标签: 防盲 项目管理 项目合作
  • 简介:AIM:Toaddressissuesininteroperabilitybetweendifferentfundusimagesystems,weproposedawebeyepicturearchivingandcommunicationsystem(PACS)frameworkinconformancewithdigitalimagingandcommunicationinmedicine(DICOM)andhealthlevel7(HL7)protocoltorealizefundusimagesandreportssharingandcommunicationthroughinternet.METHODS:Firstly,atelemedicine-basedeyecareworkflowwasestablishedbasedonintegratingthehealthcareenterprise(IHE)EyeCaretechnicalframework.Then,abrowser/serverarchitectureeye-PACSsystemwasestablishedinconformancewiththewebaccesstoDICOMpersistentobject(WADO)protocol,whichcontainsthreetiers.RESULTS:Inanyclientsysteminstalledwithwebbrowser,clinicianscouldlogintheeye-PACStoobservefundusimagesandreports.Multipurposeinternetmailextensions(MIME)typeofastructuredreportissavedaspdf/htmlwithreferencelinktorelevantfundusimageusingtheWADOsyntaxcouldprovideenoughinformationforclinicians.Somefunctionsprovidedbyopen-sourceOviyamcouldbeusedtoquery,zoom,move,measure,viewOICOMfundusimages.CONCLUSION:Suchwebeye-PACSincompliancetoWADOprotocolcouldbeusedtostoreandcommunicatefundusimagesandreports,thereforeisofgreatsignificanceforteleophthalmology.

  • 标签: PICTURE ARCHIVING and communication system teleophthalmology
  • 简介:  项目管理就是项目的管理者在有限的资源约束下,运用系统的观点、方法和理论,对项目涉及的全部工作进行有效的管理,以实现项目的目标.……

  • 标签: 合作项目管理 常用工具应用 管理常用工具
  • 简介:医疗系统的前景是什么?作为眼科医疗工作者,我们不仅要治疗眼睛,我们更要治疗患者。同样,眼科医疗并非在真空中作业,而是从属于更宽泛的医疗保健系统。当我们的工作需要如此之多的人力之时,很可能让人忘记工作的大背景是什么。然而,

  • 标签: 眼科医疗系统 服务 人力资源 信息
  • 简介:目的探讨自我管理项目在门诊青光眼患者中的应用及效果。方法将112例门诊青光眼患者随机分为56例对照组、56例干预组。对照组给予门诊常规药物治疗和常规健康教育指导;干预组在门诊常规药物治疗基础上,进行自我管理项目干预,比较两组病人的自我管理行为、自我效能水平和生活质量。结果干预后12周,干预组自我管理行为、自我效能水平和生活质量显著优于对照组(P〈0.05)。结论自我管理项目干预能提高青光眼患者自我管理行为、自我效能水平和生活质量。

  • 标签: 青光眼 自我管理 护理
  • 简介:·Thisisacasepresentationofaverybizarreopenglobetraumawithanteriorsegmentforeignbody-fishinghookstuckinthecorneaandiris.Complicationsduetothiskindofeyetraumamightbeveryhazardousandwithseriousimpactonvisualfunction.Wearerepresentingourapproachandexperienceofthreestepmanagementofthiskindofeyeinjury:first-extracttheforeignbody,closeandreconstructtheeyeball,second-fightinflammation,andthird-restorethevisualfunctionbycataractsurgery.·

  • 标签: eye TRAUMA ANTERIOR SEGMENT foreign body
  • 简介:目的探讨和总结“复明一号”眼科流动手术车在农村地区行白内障复明手术围手术期的管理方法。方法对“复明一号流动手术车”2012年在农村地区施行的5483例白内障手术联合人工晶体植入手术围手术期管理方法进行回顾性分析和总结。结果在“复明一号”眼科流动手术车上施行的5483例白内障复明手术无一例严重的术中术后并发症发生。结论在眼科流动手术车上施行大规模白内障复明手术除严格遵守常规的围手术期护理方法外,还要结合农村地区的条件和在车上进行手术的特点制定实施围手术期管理方法,以减少手术并发症,使白内障复明手术安全高效。

  • 标签: “复明一号” 眼科流动手术车 围手术期管理 白内障
  • 简介:AIM:Tocomparetheeffectoftopicallyadministeredandsubconjunctivallyinjectedbevacizumabonexperimentalcornealneovascularizationinratsfortwoweeksaftertreatment.METHODS:Twenty-eightSprague-Dawleyratsweredividedintofourgroupsof7animals.Eachcornealcenterofrighteyewascauterizedwithsilver/potassiumnitratefor8s.Aftercornealburning,bevacizumab(12.5mg/mL)wastopicallyadministeredthreetimesperday(TBgroup)fortwoweeksorsubconjunctivallyinjectedondays2and4aftercauterization(0.02mL;SBgroup).Asnegativecontrols,ratsreceived0.9%salinetopicallythreetimesperday(TSgroup)orsubconjunctivallyondays2and4(0.02mL;SSgroup).Digitalphotographsofthecorneaweretaken1and2weeksaftertreatmentandanalyzedtodeterminetheareaofcorneacoveredbyneovascularizationasthepercentageofcornealneovascularization.RESULTS:Oneweekaftertreatment,thepercentageofcornealneovascularizationwassignificantlylowerintheTBandSBgroupsthanintheTSandSSgroups(allP<0.05).Twoweeksaftertreatment,thepercentageofcornealneovascularizationwassignificantlylowerintheTBgroupthanintheTSgroup(P<0.05).Inallgroups,thepercentageofneovascularizationwasdecreasingastimepassed(allP<0.05)CONCLUSION:Topicallyadministeredbevacizumabhaslongerstandinganti-angiogeniceffectthansubconjunctivallyinjectedbevacizumabincornealneovascularizationfollowingchemicalinjuryinrats.

  • 标签: CORNEAL NEOVASCULARIZATION BEVACIZUMAB TOPICAL and SUBCONJUNCTIVAL